Guiding the choice of informatics software and tools for lipidomics research applications

Z Ni, M Wölk, G Jukes, K Mendivelso Espinosa… - Nature …, 2023 - nature.com
Progress in mass spectrometry lipidomics has led to a rapid proliferation of studies across
biology and biomedicine. These generate extremely large raw datasets requiring …

[HTML][HTML] Lipoxidation in cardiovascular diseases

E Gianazza, M Brioschi, AM Fernandez, C Banfi - Redox biology, 2019 - Elsevier
Lipids can go through lipid peroxidation, an endogenous chain reaction that consists in the
oxidative degradation of lipids leading to the generation of a wide variety of highly reactive …

CEU mass mediator 3.0: a metabolite annotation tool

A Gil-de-la-Fuente, J Godzien, S Saugar… - Journal of proteome …, 2018 - ACS Publications
CEU Mass Mediator (CMM, http://ceumass. eps. uspceu. es) is an online tool that has
evolved from a simple interface to query different metabolomic databases (CMM 1.0) to a …

Lipidr: a software tool for data mining and analysis of lipidomics datasets

A Mohamed, J Molendijk, MM Hill - Journal of proteome research, 2020 - ACS Publications
The rapid evolution of mass spectrometry (MS)-based lipidomics has enabled the
simultaneous measurement of numerous lipid classes. With lipidomics datasets becoming …

Structural library and visualization of endogenously oxidized phosphatidylcholines using mass spectrometry-based techniques

Y Matsuoka, M Takahashi, Y Sugiura, Y Izumi… - Nature …, 2021 - nature.com
Although oxidized phosphatidylcholines (oxPCs) play critical roles in numerous pathological
events, the type and production sites of endogenous oxPCs remain unknown because of the …

Targeting oxidized phospholipids by AAV-based gene therapy in mice with established hepatic steatosis prevents progression to fibrosis

CM Upchurch, S Yeudall, CM Pavelec, D Merk… - Science …, 2022 - science.org
Oxidized phosphatidylcholines (OxPCs) are implicated in chronic tissue damage.
Hyperlipidemic LDL-R-–deficient mice transgenic for an OxPC-recognizing IgM fragment …

A review of efforts to improve lipid stability during sample preparation and standardization efforts to ensure accuracy in the reporting of lipid measurements

CZ Ulmer, JP Koelmel, CM Jones, TJ Garrett… - Lipids, 2021 - Wiley Online Library
Lipidomics is a rapidly growing field, fueled by developments in analytical instrumentation
and bioinformatics. To date, most researchers and industries have employed their own …

Metal ion-mediated pro-oxidative reactions of different lipid molecules: Revealed by nontargeted lipidomic approaches

Z Zhou, YY Zhang, R **n, XH Huang, YL Li… - Journal of agricultural …, 2022 - ACS Publications
Unsaturated fatty acids are easily affected by metal ions, leading to the changes of their
flavor, nutrition, and safety through lipid oxidation. Nevertheless, there is a lack of …

[HTML][HTML] Keratinocyte death by ferroptosis initiates skin inflammation after UVB exposure

K Vats, O Kruglov, A Mizes, SN Samovich… - Redox Biology, 2021 - Elsevier
The ultraviolet B radiation (UVB) causes skin inflammation, which contributes to the causality
and the exacerbation of a number of cutaneous diseases. However, the mechanism of UVB …

Unraveling the thermal oxidation products and peroxidation mechanisms of different chemical structures of lipids: An example of molecules containing oleic acid

Z Zhou, YL Li, F Zhao, R **n, XH Huang… - Journal of Agricultural …, 2022 - ACS Publications
Lipid structures affect lipid oxidation, causing differences in types and contents of volatiles
and nonvolatiles in various foods. In this study, the oxidation differences of monoacylglycerol …