Cardiovascular effects of marijuana and synthetic cannabinoids: the good, the bad, and the ugly

P Pacher, S Steffens, G Haskó, TH Schindler… - Nature Reviews …, 2018 - nature.com
Dysregulation of the endogenous lipid mediators endocannabinoids and their G-protein-
coupled cannabinoid receptors 1 and 2 (CB1R and CB2R) has been implicated in a variety …

From phytocannabinoids to cannabinoid receptors and endocannabinoids: pleiotropic physiological and pathological roles through complex pharmacology

A Ligresti, L De Petrocellis… - Physiological …, 2016 - journals.physiology.org
Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …

Clinical quantification of myocardial blood flow using PET: joint position paper of the SNMMI cardiovascular council and the ASNC

VL Murthy, TM Bateman, RS Beanlands, DS Berman… - 2018 - Springer
Radionuclide myocardial perfusion imaging (MPI) is among the most commonly performed
diagnostic tests in cardiology. Although the diagnostic and prognostic applications of …

EANM procedural guidelines for PET/CT quantitative myocardial perfusion imaging

R Sciagrà, M Lubberink, F Hyafil, A Saraste… - European journal of …, 2021 - Springer
The use of cardiac PET, and in particular of quantitative myocardial perfusion PET, has been
growing during the last years, because scanners are becoming widely available and …

Modulating the endocannabinoid system in human health and disease–successes and failures

P Pacher, G Kunos - The FEBS journal, 2013 - Wiley Online Library
The discovery of the endocannabinoid system, comprising the G‐protein coupled
cannabinoid 1 and 2 receptors (CB 1/2), their endogenous lipid ligands or …

Coronary microvascular dysfunction: clinical considerations and noninvasive diagnosis

TH Schindler, V Dilsizian - Cardiovascular imaging, 2020 - jacc.org
Chest pain in patients without obstructive coronary artery disease has been realized as a
frequent problem encountered in clinical practice. Invasive flow investigations have …

Cardiovascular complications of marijuana and related substances: a review

A Singh, S Saluja, A Kumar, S Agrawal, M Thind… - Cardiology and …, 2018 - Springer
The recreational use of cannabis has sharply increased in recent years in parallel with its
legalization and decriminalization in several countries. Commonly, the traditional cannabis …

[HTML][HTML] Multifactorial basis and therapeutic strategies in metabolism-related diseases

JVS Guerra, MMG Dias, AJVC Brilhante, MF Terra… - Nutrients, 2021 - mdpi.com
Throughout the 20th and 21st centuries, the incidence of non-communicable diseases
(NCDs), also known as chronic diseases, has been increasing worldwide. Changes in …

Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy

M Rajesh, S Bátkai, M Kechrid, P Mukhopadhyay… - Diabetes, 2012 - diabetesjournals.org
Endocannabinoids and cannabinoid 1 (CB1) receptors have been implicated in cardiac
dysfunction, inflammation, and cell death associated with various forms of shock, heart …

Role of the endocannabinoid system in diabetes and diabetic complications

G Gruden, F Barutta, G Kunos… - British journal of …, 2016 - Wiley Online Library
Increasing evidence suggests that an overactive endocannabinoid system (ECS) may
contribute to the development of diabetes by promoting energy intake and storage, impairing …