[HTML][HTML] Biomarkers of mitochondrial dysfunction in autism spectrum disorder: A systematic review and meta-analysis

RE Frye, N Rincon, PJ McCarty, D Brister… - Neurobiology of …, 2024 - Elsevier
Autism spectrum disorder (ASD) is a neurodevelopmental disorder affecting 1 in 36 children
and is associated with physiological abnormalities, most notably mitochondrial dysfunction …

Bridging Genetic Insights with Neuroimaging in Autism Spectrum Disorder—A Systematic Review

J Vilela, C Rasga, JX Santos, H Martiniano… - International Journal of …, 2024 - mdpi.com
Autism Spectrum Disorder (ASD) is an early onset neurodevelopmental disorder
characterized by impaired social interaction and communication, and repetitive patterns of …

Metabolic network analysis of pre-ASD newborns and 5-year-old children with autism spectrum disorder

SS Lingampelly, JC Naviaux, LS Heuer… - Communications …, 2024 - nature.com
Classical metabolomic and new metabolic network methods were used to study the
developmental features of autism spectrum disorder (ASD) in newborns (n= 205) and 5-year …

Sex mechanisms as nonbinary influences on cognitive diversity

NM Grissom, N Glewwe, C Chen, E Giglio - Hormones and Behavior, 2024 - Elsevier
Essentially all neuropsychiatric diagnoses show some degree of sex and/or gender
differences in their etiology, diagnosis, or prognosis. As a result, the roles of sex-related …

Rare variation in non-coding regions with evolutionary signatures contributes to autism spectrum disorder risk

T Shin, JHT Song, M Kosicki, C Kenny, SG Beck… - Cell Genomics, 2024 - cell.com
Little is known about the role of non-coding regions in the etiology of autism spectrum
disorder (ASD). We examined three classes of non-coding regions: human accelerated …

Are there distinct levels of language comprehension in autistic individuals–cluster analysis

A Vyshedskiy, R Venkatesh… - Npj Mental Health …, 2024 - nature.com
Autism is a neurodevelopmental condition characterized by deficits in social communication.
We assessed 14-language comprehension abilities in 31,845 autistic individuals 4 to 21 …

Studies assessing domains pertaining to structural language in autism vary in reporting practices and approaches to assessment: A systematic review

T Girolamo, L Shen, A Monroe Gulick, ML Rice… - …, 2024 - journals.sagepub.com
Language in autism is heterogeneous, with a significant proportion of individuals having
structural language difficulties and inclusion of language impairment as a specifier under …

Strategies for dissecting the complexity of neurodevelopmental disorders

J Sun, S Noss, D Banerjee, M Das, S Girirajan - Trends in Genetics, 2024 - cell.com
Neurodevelopmental disorders (NDDs) are associated with a wide range of clinical features,
affecting multiple pathways involved in brain development and function. Recent advances in …

Whole genome sequencing analysis identifies sex differences of familial pattern contributing to phenotypic diversity in autism

SW Kim, H Lee, DY Song, GH Lee, J Ji, JW Park… - Genome Medicine, 2024 - Springer
Background Whole-genome sequencing (WGS) analyses have found higher genetic burden
in autistic females compared to males, supporting higher liability threshold in females …

The Importance of Large-Scale Genomic Studies to Unravel Genetic Risk Factors for Autism

IS Nóbrega, AL Teles e Silva… - International Journal of …, 2024 - mdpi.com
Autism spectrum disorder (ASD) is a common and highly heritable neurodevelopmental
disorder. During the last 15 years, advances in genomic technologies and the availability of …