Synaptic plasticity: multiple forms, functions, and mechanisms

A Citri, RC Malenka - Neuropsychopharmacology, 2008 - nature.com
Experiences, whether they be learning in a classroom, a stressful event, or ingestion of a
psychoactive substance, impact the brain by modifying the activity and organization of …

Synaptic computation

LF Abbott, WG Regehr - Nature, 2004 - nature.com
Neurons are often considered to be the computational engines of the brain, with synapses
acting solely as conveyers of information. But the diverse types of synaptic plasticity and the …

Synaptic scaling mediated by glial TNF-α

D Stellwagen, RC Malenka - Nature, 2006 - nature.com
Two general forms of synaptic plasticity that operate on different timescales are thought to
contribute to the activity-dependent refinement of neural circuitry during development:(1) …

What is neural plasticity?

R Von Bernhardi, LE Bernhardi, J Eugenín - The plastic brain, 2017 - Springer
Abstract “Neural plasticity” refers to the capacity of the nervous system to modify itself,
functionally and structurally, in response to experience and injury. As the various chapters in …

Activity-dependent relocation of the axon initial segment fine-tunes neuronal excitability

MS Grubb, J Burrone - Nature, 2010 - nature.com
In neurons, the axon initial segment (AIS) is a specialized region near the start of the axon
that is the site of action potential initiation,,,,,. The precise location of the AIS varies across …

Evidence for a cytokine model of cognitive function

J McAfoose, BT Baune - Neuroscience & Biobehavioral Reviews, 2009 - Elsevier
Aiming at a formulation of a cytokine model of cognitive function under immunologically
unchallenged physiological conditions, this article reviews the cytokine biology in the central …

[HTML][HTML] Unraveling mechanisms of homeostatic synaptic plasticity

K Pozo, Y Goda - Neuron, 2010 - cell.com
Homeostatic synaptic plasticity is a negative feedback mechanism that neurons use to offset
excessive excitation or inhibition by adjusting their synaptic strengths. Recent findings …

An integrative model of tinnitus based on a central gain controlling neural sensitivity

AJ Noreña - Neuroscience & Biobehavioral Reviews, 2011 - Elsevier
The purpose of the current review is to propose a model highlighting the putative
connections between hearing loss and the phantom perception of tinnitus (tinnitus being …

Alterations of GABAergic signaling in autism spectrum disorders

R Pizzarelli, E Cherubini - Neural plasticity, 2011 - Wiley Online Library
Autism spectrum disorders (ASDs) comprise a heterogeneous group of pathological
conditions, mainly of genetic origin, characterized by stereotyped behavior, marked …

Homeostatic control of neural activity: from phenomenology to molecular design

GW Davis - Annu. Rev. Neurosci., 2006 - annualreviews.org
Homeostasis is a specialized form of regulation that precisely maintains the function of a
system at a set point level of activity. Recently, homeostatic signaling has been suggested to …