Alzheimer's disease (AD) is a neurodegenerative disorder that impairs mental ability
development and interrupts neurocognitive function. This neuropathological condition is …

Big data in health care is a fast-growing field and a new paradigm that is transforming case-
based studies to large-scale, data-driven research. As big data is dependent on the …

Drug repurposing is a strategy consisting of finding new indications for already known
marketed drugs used in various clinical settings or highly characterized compounds despite …

Background Alzheimer's disease (AD) is a neurodegenerative disease and the most
common cause of dementia. In this umbrella systematic review (SR), we summarized the …

The present article reviews published efforts to study acetylcholinesterase and
butyrylcholinesterase structure and function using computer-based modeling and simulation …

Abstract Non-Structural Protein 16 (nsp-16), a viral RNA methyltransferase (MTase), is one
of the highly viable targets for drug discovery of coronaviruses including SARS-CoV-2. In …

SwissDrugDesign is an important initiative led by the Molecular Modeling Group of the SIB
Swiss Institute of Bioinformatics. This project provides a collection of freely available online …

Hit finding, scaffold hop**, and structure–activity relationship studies are important tasks in
rational drug discovery. Implementation of these tasks strongly depends on the availability of …

Alzheimer's disease (AD) is recognized as a major health hazard that mostly affects people
older than 60 years. AD is one of the biggest medical, economic, and social concerns to …

Salt-tolerant plants, also known as halophytes, could provide a novel source of feedstock for
biorefineries. After harvesting fresh shoots for food, the lignified fraction of Salicornia …