Various non-nucleic acid targets (ions, small molecules, polysaccharides, peptides/proteins/
enzymes, cells, transcription factors) are important biomarkers. They play important roles in …

The World Health Organization (WHO) estimated that pathogens like Escherichia coli,
primarily linked to food and water contamination, are associated with 485,000 deaths from …

Nucleic acid cleavage processes contribute to target and signal amplification, which is
critical for the development of highly sensitive assays. 1, 2 Exonucleases or endonucleases …

Background Schistosomiasis is a disease that significantly impacts human health in the
develo** world. Effective diagnostics are urgently needed for improved control of this …

Abstract The fusion of Rolling Circle Amplification (RCA) and the Clustered Regularly
Interspaced Short Palindromic Repeats–CRISPR-associated proteins (CRISPR-Cas) stands …

The exceptional programable trans-cleavage ability of type V and VI CRISPR/Cas nucleases
paved the way for ultrasensitive CRISPR/Cas based sensing of nucleic acid and alternative …

Lumpy skin disease (LSD) is a severe and highly infectious pox disease of cattle caused by
the lumpy skin disease virus (LSDV). To facilitate early control of LSD, this study aimed to …

Polychlorinated biphenyls (PCBs) are ubiquitous persistent organic pollutants that cause
harmful effects on environmental safety and human health. There is an urgent need to …

Molecular diagnostic (MDx) methods directly detect target nucleic acid sequences and are
therefore an important approach for precise diagnosis of pathogen infection. In comparison …

In this work, an electrochemiluminescence (ECL) biosensor with dual signal enhancement
was constructed and used for DNA adenine methylation methyltransferase (Dam MTase) …