Nontuberculous mycobacteria (NTM) are increasingly recognized as causative agents of
opportunistic infections in humans. For most NTM infections the therapy of choice is drug …

Introduction: One-third of the world's population is infected with Mycobacterium tuberculosis
(M. tb.). Latent tuberculosis infection (LTBI) can progress to tuberculosis disease, the leading …

Background Buruli ulcer is a neglected tropical disease caused by Mycobacterium ulcerans
infection that damages the skin and subcutis. It is most prevalent in western and central …

Rationale: Currently recommended multidrug treatment regimens for Mycobacterium avium
complex (MAC) lung disease yield limited cure rates. This results, in part, from incomplete …

Introduction Rifampicin (RIF) and clarithromycin (CLR) are common drugs for the treatment
of infections like Mycobacterium tuberculosis and Mycobacterium ulcerans. Treatment for …

Non-tuberculous mycobacteria (NTM) are acid-fast bacteria that are ubiquitous in the
environment and can colonize soil, dust particles, water sources, and food supplies. They …

Like any other drug, antimicrobial drugs are prone to pharmacokinetic drug interactions.
These drug interactions are a major concern in clinical practice as they may have an effect …

Background Buruli ulcer is a necrotizing cutaneous infection caused by infection with
Mycobacterium ulcerans bacteria that occurs mainly in tropical and subtropical regions. The …

Buruli ulcer, an ulcerating skin disease caused by Mycobacterium ulcerans infection, is
common in tropical areas of western Africa. We determined the clinical and microbiological …

Abstract Introduction Neglected tropical diseases (NTDs) affect more than one billion
people, mainly living in develo** countries. For most of these NTDs, treatment is …