The concept and development of bone/cartilage organoids are rapidly gaining momentum,
providing opportunities for both fundamental and translational research in bone biology …

Clinical therapeutics for the regeneration of osteochondral defects (OCD) in the early stages
of osteoarthritis remain an enormous challenge in orthopaedics. For in-depth studies of …

Cartilage tissue presents low self‐repair capability and lesions often undergo irreversible
progression. Structures obtained by tissue engineering, such as those based in extrusion …

Articular cartilage lesion such as osteoarthritis (OA) is becoming a serious threat to global
human health. In recent years, as a new paradigm in cartilage tissue engineering and …

Endochondral ossification (EO) is an essential biological process than underpins how
human bones develop, grow, and heal in the event of a fracture. So much is unknown about …

Osteochondral tissue regeneration is quite difficult to achieve due to the complexity of its
organization. In the design of these complex multilayer structures, a fabrication method, 3D …

Articular cartilage damage caused by trauma or degenerative pathologies such as
osteoarthritis can result in significant pain, mobility issues, and disability. Current surgical …

Tracheal defects lead to devastating problems, and practical clinical substitutes that have
complex functional structures and can avoid adverse influences from exogenous …

Despite promising clinical results in osteochondral defect repair, a recently developed bi-
layered collagen/collagen-magnesium-hydroxyapatite scaffold has demonstrated less …

Background A significant hurdle for potential cell‐based therapies is the subsequent survival
and regenerative capacity of implanted cells. While many exciting developments have …