Histamine intolerance originates in the gut

WJ Schnedl, D Enko - Nutrients, 2021 - mdpi.com
Histamine intolerance (HIT) is assumed to be due to a deficiency of the gastrointestinal (GI)
enzyme diamine oxidase (DAO) and, therefore, the food component histamine not being …

The interplay among gut microbiota, hypertension and kidney diseases: The role of short-chain fatty acids

RJF Felizardo, IKM Watanabe, P Dardi… - Pharmacological …, 2019 - Elsevier
The bacteria community living in the gut maintains a symbiotic relationship with the host and
its unbalance has been associated with progression of a wide range of intestinal and extra …

DRAM for distilling microbial metabolism to automate the curation of microbiome function

M Shaffer, MA Borton, BB McGivern… - Nucleic acids …, 2020 - academic.oup.com
Microbial and viral communities transform the chemistry of Earth's ecosystems, yet the
specific reactions catalyzed by these biological engines are hard to decode due to the …

Rational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization

FC Pereira, K Wasmund, I Cobankovic… - Nature …, 2020 - nature.com
Many intestinal pathogens, including Clostridioides difficile, use mucus-derived sugars as
crucial nutrients in the gut. Commensals that compete with pathogens for such nutrients are …

Mendelian randomization analyses support causal relationships between blood metabolites and the gut microbiome

X Liu, X Tong, Y Zou, X Lin, H Zhao, L Tian, Z Jie… - Nature …, 2022 - nature.com
The gut microbiome has been implicated in a variety of physiological states, but controversy
over causality remains unresolved. Here, we performed bidirectional Mendelian …

Gut bacterial nutrient preferences quantified in vivo

X Zeng, X **ng, M Gupta, FC Keber, JG Lopez… - Cell, 2022 - cell.com
Great progress has been made in understanding gut microbiomes' products and their effects
on health and disease. Less attention, however, has been given to the inputs that gut …

Dietary carbohydrates regulate intestinal colonization and dissemination of Klebsiella pneumoniae

AL Hecht, LC Harling, ES Friedman, C Tanes… - The Journal of Clinical …, 2024 - jci.org
Bacterial translocation from the gut microbiota is a source of sepsis in susceptible patients.
Previous work suggests that overgrowth of gut pathobionts, including Klebsiella …

Microbiota responses to different prebiotics are conserved within individuals and associated with habitual fiber intake

ZC Holmes, MM Villa, HK Durand, S Jiang, EP Dallow… - Microbiome, 2022 - Springer
Background Short-chain fatty acids (SCFAs) derived from gut bacteria are associated with
protective roles in diseases ranging from obesity to colorectal cancers. Intake of microbially …

MICOM: metagenome-scale modeling to infer metabolic interactions in the gut microbiota

C Diener, SM Gibbons, O Resendis-Antonio - MSystems, 2020 - journals.asm.org
Compositional changes in the gut microbiota have been associated with a variety of medical
conditions such as obesity, Crohn's disease, and diabetes. However, connecting microbial …

Growth promotion and antibiotic induced metabolic shifts in the chicken gut microbiome

G Plata, NT Baxter, D Susanti… - Communications …, 2022 - nature.com
Antimicrobial growth promoters (AGP) have played a decisive role in animal agriculture for
over half a century. Despite mounting concerns about antimicrobial resistance and demand …