DRAM for distilling microbial metabolism to automate the curation of microbiome function
Microbial and viral communities transform the chemistry of Earth's ecosystems, yet the
specific reactions catalyzed by these biological engines are hard to decode due to the …
specific reactions catalyzed by these biological engines are hard to decode due to the …
[HTML][HTML] Adaptation of the gut microbiota to modern dietary sugars and sweeteners
The consumption of sugar has become central to the Western diet. Cost and health concerns
associated with sucrose spurred the development and consumption of other sugars and …
associated with sucrose spurred the development and consumption of other sugars and …
Holo-omics: integrated host-microbiota multi-omics for basic and applied biological research
From ontogenesis to homeostasis, the phenotypes of complex organisms are shaped by the
bidirectional interactions between the host organisms and their associated microbiota …
bidirectional interactions between the host organisms and their associated microbiota …
Rational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization
Many intestinal pathogens, including Clostridioides difficile, use mucus-derived sugars as
crucial nutrients in the gut. Commensals that compete with pathogens for such nutrients are …
crucial nutrients in the gut. Commensals that compete with pathogens for such nutrients are …
Mendelian randomization analyses support causal relationships between blood metabolites and the gut microbiome
X Liu, X Tong, Y Zou, X Lin, H Zhao, L Tian, Z Jie… - Nature …, 2022 - nature.com
The gut microbiome has been implicated in a variety of physiological states, but controversy
over causality remains unresolved. Here, we performed bidirectional Mendelian …
over causality remains unresolved. Here, we performed bidirectional Mendelian …
Gut bacterial nutrient preferences quantified in vivo
Great progress has been made in understanding gut microbiomes' products and their effects
on health and disease. Less attention, however, has been given to the inputs that gut …
on health and disease. Less attention, however, has been given to the inputs that gut …
Metabolic landscape of the male mouse gut identifies different niches determined by microbial activities
Distinct niches of the mammalian gut are populated by diverse microbiota, but the
contribution of spatial variation to intestinal metabolism remains unclear. Here we present a …
contribution of spatial variation to intestinal metabolism remains unclear. Here we present a …
Growth promotion and antibiotic induced metabolic shifts in the chicken gut microbiome
Antimicrobial growth promoters (AGP) have played a decisive role in animal agriculture for
over half a century. Despite mounting concerns about antimicrobial resistance and demand …
over half a century. Despite mounting concerns about antimicrobial resistance and demand …
MICOM: metagenome-scale modeling to infer metabolic interactions in the gut microbiota
Compositional changes in the gut microbiota have been associated with a variety of medical
conditions such as obesity, Crohn's disease, and diabetes. However, connecting microbial …
conditions such as obesity, Crohn's disease, and diabetes. However, connecting microbial …
Microbiota responses to different prebiotics are conserved within individuals and associated with habitual fiber intake
Background Short-chain fatty acids (SCFAs) derived from gut bacteria are associated with
protective roles in diseases ranging from obesity to colorectal cancers. Intake of microbially …
protective roles in diseases ranging from obesity to colorectal cancers. Intake of microbially …