Fractionating impulsivity: neuropsychiatric implications

JW Dalley, TW Robbins - Nature Reviews Neuroscience, 2017 - nature.com
The ability to make decisions and act quickly without hesitation can be advantageous in
many settings. However, when persistently expressed, impulsive decisions and actions are …

Functional heterogeneity within rat orbitofrontal cortex in reward learning and decision making

A Izquierdo - Journal of Neuroscience, 2017 - Soc Neuroscience
Rat orbitofrontal cortex (OFC) is located in the dorsal bank of the rhinal sulcus, and is
divided into the medial orbital area, ventral orbital area, ventrolateral orbital area, lateral …

Impulsivity, compulsivity, and top-down cognitive control

JW Dalley, BJ Everitt, TW Robbins - Neuron, 2011 - cell.com
Impulsivity is the tendency to act prematurely without foresight. Behavioral and
neurobiological analysis of this construct, with evidence from both animal and human …

[HTML][HTML] Dopamine, serotonin and impulsivity

JW Dalley, JP Roiser - Neuroscience, 2012 - Elsevier
Impulsive people have a strong urge to act without thinking. It is sometimes regarded as a
positive trait but rash impulsiveness is also widely present in clinical disorders such as …

Emotion regulation and impulsivity in young adults

LRN Schreiber, JE Grant, BL Odlaug - Journal of psychiatric research, 2012 - Elsevier
Past research has linked both emotion regulation and impulsivity with the development and
maintenance of addictions. However, no research has investigated the relationship between …

Prefrontal dopamine and behavioral flexibility: shifting from an “inverted-U” toward a family of functions

SB Floresco - Frontiers in neuroscience, 2013 - frontiersin.org
Studies on prefrontal cortex (PFC) dopamine (DA) function have revealed its essential role
in mediating a variety of cognitive and executive functions. A general principle that has …

An analysis of rat prefrontal cortex in mediating executive function

RP Kesner, JC Churchwell - Neurobiology of learning and memory, 2011 - Elsevier
While it is acknowledged that species specific differences are an implicit condition of
comparative studies, rodent models of prefrontal function serve a significant role in the …

Insight into the relationship between impulsivity and substance abuse from studies using animal models

CA Winstanley, P Olausson, JR Taylor… - Alcoholism: Clinical …, 2010 - Wiley Online Library
Drug use disorders are often accompanied by deficits in the capacity to efficiently process
reward‐related information and to monitor, suppress, or override reward‐controlled behavior …

The utility of rat models of impulsivity in develo** pharmacotherapies for impulse control disorders

CA Winstanley - British journal of pharmacology, 2011 - Wiley Online Library
High levels of impulsive behaviours are a clinically significant symptom in a range of
psychiatric disorders, such as attention deficit hyperactivity disorder, bipolar disorder …

Behavioral modeling of human choices reveals dissociable effects of physical effort and temporal delay on reward devaluation

MC Klein-Flügge, SW Kennerley… - PLoS computational …, 2015 - journals.plos.org
There has been considerable interest from the fields of biology, economics, psychology, and
ecology about how decision costs decrease the value of rewarding outcomes. For example …