[HTML][HTML] Overcoming Cancer Drug Resistance with Nanoparticle Strategies for Key Protein Inhibition

H Yoo, Y Kim, J Kim, H Cho, K Kim - Molecules, 2024 - mdpi.com
Drug resistance remains a critical barrier in cancer therapy, diminishing the effectiveness of
chemotherapeutic, targeted, and immunotherapeutic agents. Overexpression of proteins …

[HTML][HTML] Biorobotic Drug Delivery for Biomedical Applications

QV Le, G Shim - Molecules, 2024 - mdpi.com
Despite extensive efforts, current drug-delivery systems face biological barriers and
difficulties in bench-to-clinical use. Biomedical robotic systems have emerged as a new …

Immune modulation of the liver metastatic colorectal cancer microenvironment via the oral CAPOX-mediated cGAS-STING pathway

SJ Park, S Kweon, MK Moyo, HR Kim, JU Choi, NK Lee… - Biomaterials, 2024 - Elsevier
We evaluated modulation of the immunosuppressive tumor microenvironment in both local
and liver metastatic colorectal cancer (LMCC), focusing on tumor-associated macrophages …

Nano-Delivery of Immunogenic Cell Death Inducers and Immune Checkpoint Blockade Agents: Single-Nanostructure Strategies for Enhancing Immunotherapy

Y Moon, H Cho, K Kim - Pharmaceutics, 2024 - mdpi.com
Cancer immunotherapy has revolutionized oncology by harnessing the patient's immune
system to target and eliminate cancer cells. However, immune checkpoint blockades (ICBs) …

[HTML][HTML] Nanotechnology-Based Strategies for Safe and Effective Immunotherapy

S Hong, J Park, Y Oh, H Cho, K Kim - Molecules, 2024 - mdpi.com
Cancer immunotherapy using immune checkpoint blockades has emerged as a promising
therapeutic approach. However, immunotherapy faces challenges such as low response …

Catechol-modified stabilizer facilitates impulsive ligand functionalization of particulates and membrane modification of cells

P Shrestha, S Pathak, S Regmi, YS Youn… - Journal of Drug Delivery …, 2024 - Elsevier
Ligand-functionalized particulates have received considerable attention for targeted drug
delivery. Previous studies have reported several methods for functionalizing various …