Biology of the p21-activated kinases
GM Bokoch - Annual review of biochemistry, 2003 - annualreviews.org
▪ Abstract The p21-activated kinases (PAKs) 1–3 are serine/threonine protein kinases whose
activity is stimulated by the binding of active Rac and Cdc42 GTPases. Our understanding of …
activity is stimulated by the binding of active Rac and Cdc42 GTPases. Our understanding of …
MAP Kinase Pathways in the YeastSaccharomyces cerevisiae
MC Gustin, J Albertyn, M Alexander… - … and Molecular biology …, 1998 - Am Soc Microbiol
SUMMARY A cascade of three protein kinases known as a mitogen-activated protein kinase
(MAPK) cascade is commonly found as part of the signaling pathways in eukaryotic cells …
(MAPK) cascade is commonly found as part of the signaling pathways in eukaryotic cells …
[HTML][HTML] Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiae
RE Chen, J Thorner - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2007 - Elsevier
Signaling pathways that activate different mitogen-activated protein kinases (MAPKs) elicit
many of the responses that are evoked in cells by changes in certain environmental …
many of the responses that are evoked in cells by changes in certain environmental …
Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway* S
Cellular processes such as proliferation, differentiation, and adaptation to environmental
changes are regulated by protein phosphorylation. Development of sensitive and …
changes are regulated by protein phosphorylation. Development of sensitive and …
The Ste20 group kinases as regulators of MAP kinase cascades
I Dan, NM Watanabe, A Kusumi - Trends in cell biology, 2001 - cell.com
Abstract Ste20p (sterile 20 protein) is a putative yeast mitogen-activated protein kinase
kinase kinase kinase (MAP4K) involved in the mating pathway. Its homologs in mammals …
kinase kinase kinase (MAP4K) involved in the mating pathway. Its homologs in mammals …
A walk-through of the yeast mating pheromone response pathway
L Bardwell - Peptides, 2005 - Elsevier
The intracellular signal transduction pathway by which the yeast Saccharomyces cerevisiae
responds to the presence of peptide mating pheromone in its surroundings is one of the best …
responds to the presence of peptide mating pheromone in its surroundings is one of the best …
Cdc42: an essential Rho-type GTPase controlling eukaryotic cell polarity
DI Johnson - Microbiology and Molecular Biology Reviews, 1999 - Am Soc Microbiol
Cdc42p is an essential GTPase that belongs to the Rho/Rac subfamily of Ras-like GTPases.
These proteins act as molecular switches by responding to exogenous and/or endogenous …
These proteins act as molecular switches by responding to exogenous and/or endogenous …
G protein βγ subunits: central mediators of G protein-coupled receptor signaling
AV Smrcka - Cellular and molecular life sciences, 2008 - Springer
G protein βγ subunits are central participants in G protein-coupled receptor signaling
pathways. They interact with receptors, G protein α subunits and downstream targets to …
pathways. They interact with receptors, G protein α subunits and downstream targets to …
Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch
The p21-activated kinases (PAKs), stimulated by binding with GTP-liganded forms of Cdc42
or Rac, modulate cytoskeletal actin assembly and activate MAP-kinase pathways. The 2.3 Å …
or Rac, modulate cytoskeletal actin assembly and activate MAP-kinase pathways. The 2.3 Å …
Polarization of cell growth in yeast II. The role of the cortical actin cytoskeleton
D Pruyne, A Bretscher - Journal of cell science, 2000 - journals.biologists.com
The actin cytoskeleton provides the structural basis for cell polarity in Saccharomyces
cerevisiae as well as most other eukaryotes. In Part I of this two-part commentary, presented …
cerevisiae as well as most other eukaryotes. In Part I of this two-part commentary, presented …