The development of the vertebrate eyes is a complex process starting from anterior-posterior
and dorso-ventral patterning of the anterior neural tube, resulting in the formation of the eye …

Precise gene expression ensures proper stem and progenitor cell differentiation, lineage
commitment and organogenesis during mammalian development. ATP-dependent …

Multipotent retinal progenitors undergo a varied number of divisions to produce clones of
heterogeneous sizes and cell types. We describe the transition from a proliferating …

Over the last decade, the use of the zebrafish as a genetic model has moved beyond the
proof-of-concept for the analysis of vertebrate embryonic development to demonstrated …

Dominant mutations in cardiac transcription factor genes cause human inherited congenital
heart defects (CHDs); however, their molecular basis is not understood. Interactions …

Zebrafish are an increasingly popular vertebrate model organism in which to study
biological phenomena. It has been widely used, especially in developmental biology and …

SNF2 chromatin-remodeling ATPases play an important role in ensuring proper
development in higher eukaryotes by controlling accessibility of cis-regulatory DNA regions …

Chromatin remodeling complexes play crucial roles in transcription and are implicated in
processes including cell proliferation, differentiation and embryonic patterning. Brg1 is the …

The mature, functional, and healthy eye is generated by the coordinated regulatory
interaction of numerous and diverse develo** tissues. The neural retina of the eye must …

Recent studies demonstrated a number of links between chromatin structure, gene
expression, extracellular signaling and cellular differentiation during lens development …