Deep learning-based PET image denoising and reconstruction: a review

F Hashimoto, Y Onishi, K Ote, H Tashima… - … physics and technology, 2024 - Springer
This review focuses on positron emission tomography (PET) imaging algorithms and traces
the evolution of PET image reconstruction methods. First, we provide an overview of …

Advancements in positron emission tomography detectors: from silicon photomultiplier technology to artificial intelligence applications

JS Lee, MS Lee - PET clinics, 2024 - pet.theclinics.com
PET is an in vivo imaging device that allows the assessment of various functional and
biochemical processes occurring in the living bodies. In medicine, it is widely used for the …

Improving the timing resolution of positron emission tomography detectors using boosted learning—a residual physics approach

S Naunheim, Y Kuhl, D Schug… - IEEE transactions on …, 2023 - ieeexplore.ieee.org
Artificial intelligence (AI) is entering medical imaging, mainly enhancing image
reconstruction. Nevertheless, improvements throughout the entire processing, from signal …

Holistic evaluation of a machine learning-based timing calibration for PET detectors under varying data sparsity

S Naunheim, F Mueller, V Nadig, Y Kuhl… - Physics in Medicine …, 2024 - iopscience.iop.org
Objective. Modern PET scanners offer precise TOF information, improving the SNR of the
reconstructed images. Timing calibrations are performed to reduce the worsening effects of …

Whole reconstruction-free system design for direct positron emission imaging from image generation to attenuation correction

Y Onishi, F Hashimoto, K Ote… - IEEE Transactions on …, 2023 - ieeexplore.ieee.org
Direct positron emission imaging (dPEI), which does not require a mathematical
reconstruction step, is a next-generation molecular imaging modality. To maximize the …

Monolithic integration of metalens in silicon photomultiplier for improved photodetection efficiency

S Uenoyama, R Ota - Advanced Optical Materials, 2022 - Wiley Online Library
Silicon photomultipliers (SiPMs), consisting of 2D single‐photon avalanche diode (SPAD)
arrays, have been widely used in many applications. In a SiPM, trench structures surround …

ASICs in PET: what we have and what we need

V Nadig, S Gundacker, K Herweg, S Naunheim… - EJNMMI physics, 2025 - Springer
Background Designing positron emission tomography (PET) scanners involves several
significant challenges. These include the precise measurement of the time of arrival of …

Improving timing resolution of BGO for TOF-PET: a comparative analysis with and without deep learning

F Loignon-Houle, N Kratochwil, M Toussaint, C Lowis… - EJNMMI physics, 2025 - Springer
Background The renewed interest in BGO scintillators for TOF-PET is driven by the improved
Cherenkov photon detection with new blue-sensitive SiPMs. However, the slower …

Enhancing coincidence time resolution of PET detectors using short-time Fourier transform and residual neural network

A Muhashi, X Feng, Y Onishi, R Ota, H Liu - Nuclear Instruments and …, 2024 - Elsevier
Currently, a key metric for assessing the performance of time-of-flight positron emission
tomography (TOF-PET) detectors is the Coincidence Time Resolution (CTR). In this study …

Emphasizing Cherenkov photons from bismuth germanate by single photon response deconvolution

R Ota, K Ote - IEEE Transactions on Radiation and Plasma …, 2024 - ieeexplore.ieee.org
Bismuth germanate (BGO) has been receiving attention again because it is a potential
scintillator for future time-of-flight positron emission tomography. Owing to its optical …