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Hypromellose–A traditional pharmaceutical excipient with modern applications in oral and oromucosal drug delivery
E Mašková, K Kubová, BT Raimi-Abraham… - Journal of controlled …, 2020 - Elsevier
Hydroxypropylmethylcellulose (HPMC), also known as Hypromellose, is a traditional
pharmaceutical excipient widely exploited in oral sustained drug release matrix systems …
pharmaceutical excipient widely exploited in oral sustained drug release matrix systems …
A review: Gelatine as a bioadhesive material for medical and pharmaceutical applications
Bioadhesive polymers offer versatility to medical and pharmaceutical inventions. The
incorporation of such materials to conventional dosage forms or medical devices may confer …
incorporation of such materials to conventional dosage forms or medical devices may confer …
[HTML][HTML] Mucoadhesive buccal films based on a graft co-polymer–A mucin-retentive hydrogel scaffold
JF Alopaeus, M Hellfritzsch, T Gutowski… - European Journal of …, 2020 - Elsevier
From a patient-centric perspective, oromucosal drug delivery is highly attractive due to the
ease of administration without the need of swallowing, and improved patient safety. The aim …
ease of administration without the need of swallowing, and improved patient safety. The aim …
Overview and future potential of buccal mucoadhesive films as drug delivery systems for biologics
M Montenegro-Nicolini, JO Morales - Aaps Pharmscitech, 2017 - Springer
The main route of administration for drug products is the oral route, yet biologics are initially
developed as injectables due to their limited stability through the gastrointestinal tract and …
developed as injectables due to their limited stability through the gastrointestinal tract and …
Formulation challenges and strategies to develop pediatric dosage forms
WA Malkawi, E AlRafayah, M AlHazabreh, S AbuLaila… - Children, 2022 - mdpi.com
The development of pediatric-specific dose forms is particularly difficult due to a variety of
factors relating to pediatric population differences from adult populations. The buccal …
factors relating to pediatric population differences from adult populations. The buccal …
Oral mucosa models to evaluate drug permeability
Due to its numerous advantages, such as excellent drug accessibility, rapid absorption, and
bypass of first-pass metabolism, the route of drug administration that involves crossing the …
bypass of first-pass metabolism, the route of drug administration that involves crossing the …
[HTML][HTML] Mucoadhesive delivery system: A smart way to improve bioavailability of nutraceuticals
P Subramanian - Foods, 2021 - mdpi.com
The conventional oral administration of many nutraceuticals exhibits poor oral bioavailability
due to the harsh gastric conditions and first-pass metabolism. Oral mucosa has been …
due to the harsh gastric conditions and first-pass metabolism. Oral mucosa has been …
Natural guardians: Natural compounds as radioprotectors in cancer therapy
Cancer remains a significant global health challenge, with millions of deaths attributed to it
annually. Radiotherapy, a cornerstone in cancer treatment, aims to destroy cancer cells …
annually. Radiotherapy, a cornerstone in cancer treatment, aims to destroy cancer cells …
Can plant materials be valuable in the treatment of periodontal diseases? practical review
A Gościniak, M Paczkowska-Walendowska… - Pharmaceutics, 2021 - mdpi.com
Periodontal diseases are one of the most significant challenges in dental health. It is
estimated that only a few percent of the worldwide population have entirely healthy teeth …
estimated that only a few percent of the worldwide population have entirely healthy teeth …
Routes of drug administration
The systemic absorption of a drug depends on its physicochemical properties, the nature of
the dosage form on which it is included, and the anatomical and physiological …
the dosage form on which it is included, and the anatomical and physiological …