Hypromellose–A traditional pharmaceutical excipient with modern applications in oral and oromucosal drug delivery

E Mašková, K Kubová, BT Raimi-Abraham… - Journal of controlled …, 2020 - Elsevier
Hydroxypropylmethylcellulose (HPMC), also known as Hypromellose, is a traditional
pharmaceutical excipient widely exploited in oral sustained drug release matrix systems …

A review: Gelatine as a bioadhesive material for medical and pharmaceutical applications

A Ahmady, NHA Samah - International Journal of Pharmaceutics, 2021 - Elsevier
Bioadhesive polymers offer versatility to medical and pharmaceutical inventions. The
incorporation of such materials to conventional dosage forms or medical devices may confer …

[HTML][HTML] Mucoadhesive buccal films based on a graft co-polymer–A mucin-retentive hydrogel scaffold

JF Alopaeus, M Hellfritzsch, T Gutowski… - European Journal of …, 2020 - Elsevier
From a patient-centric perspective, oromucosal drug delivery is highly attractive due to the
ease of administration without the need of swallowing, and improved patient safety. The aim …

Overview and future potential of buccal mucoadhesive films as drug delivery systems for biologics

M Montenegro-Nicolini, JO Morales - Aaps Pharmscitech, 2017 - Springer
The main route of administration for drug products is the oral route, yet biologics are initially
developed as injectables due to their limited stability through the gastrointestinal tract and …

Formulation challenges and strategies to develop pediatric dosage forms

WA Malkawi, E AlRafayah, M AlHazabreh, S AbuLaila… - Children, 2022 - mdpi.com
The development of pediatric-specific dose forms is particularly difficult due to a variety of
factors relating to pediatric population differences from adult populations. The buccal …

Oral mucosa models to evaluate drug permeability

E Mazzinelli, I Favuzzi, A Arcovito, R Castagnola… - Pharmaceutics, 2023 - mdpi.com
Due to its numerous advantages, such as excellent drug accessibility, rapid absorption, and
bypass of first-pass metabolism, the route of drug administration that involves crossing the …

[HTML][HTML] Mucoadhesive delivery system: A smart way to improve bioavailability of nutraceuticals

P Subramanian - Foods, 2021 - mdpi.com
The conventional oral administration of many nutraceuticals exhibits poor oral bioavailability
due to the harsh gastric conditions and first-pass metabolism. Oral mucosa has been …

Natural guardians: Natural compounds as radioprotectors in cancer therapy

A Stasiłowicz-Krzemień, A Gościniak… - International Journal of …, 2024 - mdpi.com
Cancer remains a significant global health challenge, with millions of deaths attributed to it
annually. Radiotherapy, a cornerstone in cancer treatment, aims to destroy cancer cells …

Can plant materials be valuable in the treatment of periodontal diseases? practical review

A Gościniak, M Paczkowska-Walendowska… - Pharmaceutics, 2021 - mdpi.com
Periodontal diseases are one of the most significant challenges in dental health. It is
estimated that only a few percent of the worldwide population have entirely healthy teeth …

Routes of drug administration

ME Ruiz, S Scioli-Montoto - ADME processes in pharmaceutical sciences …, 2024 - Springer
The systemic absorption of a drug depends on its physicochemical properties, the nature of
the dosage form on which it is included, and the anatomical and physiological …