In recent years, experimental evidence suggested a possible role of the gut microbiota in the
onset and development of several neurodegenerative disorders, such as AD and PD, MS …

Neuropathic pain (NP) is a common chronic pain with heterogeneous clinical features, and
consequent lowering of quality of life. Currently, although conventional chemical drugs can …

Maladaptive plasticity is linked to the chronification of diseases such as pain, but the
transition from acute to chronic pain is not well understood mechanistically. Neuroplasticity …

Neuropathic pain, a chronic condition resulting from nerve injury or dysfunction, presents
significant therapeutic challenges and is closely associated with oxidative stress and …

Neuropathic pain is a debilitating condition characterized by abnormal signaling within the
nervous system, resulting in persistent and often intense sensations of pain. It can arise from …

Introduction This review highlights the critical role of the endocannabinoid system (ECS) in
regulating neuropathic pain and explores the therapeutic potential of cannabinoids …

This study examined the effects of turmeric bioactive compounds, curcumin C3
complex®(CUR) and bisdemethoxycurcumin (BDMC), on mechanical hypersensitivity and …

Background: Neuroinflammation and mitochondrial dysfunction have been implicated in the
progression of neuropathic pain (NP) but can be mitigated by supplementation with gingerol …

Oxaliplatin (OXA) has shown high effectiveness in the treatment of cancers, but its
anticancer clinical effects often induce neurotoxicity leading to neuropathic pain. Oxidative …

Objectives: Emerging evidence suggests an important role of the gut-brain axis in the
development of neuropathic pain (NP). We investigated the effects of gingerol-enriched …