Structural imaging remains an essential component of diagnosis, staging and response
assessment in patients with cancer; however, as clinicians increasingly seek to …

Ferroptosis is a type of cell death that depends on iron and reactive oxygen species (ROS).
The accumulation of iron and lipid peroxidation primarily initiates oxidative membrane …

The MTT assay for cellular metabolic activity is almost ubiquitous to studies of cell toxicity;
however, it is commonly applied and interpreted erroneously. We investigated the …

The past few years have witnessed the rise of chemodynamic therapy (CDT) as an emerging
strategy for malignant tumors suppression. Nanoplatform-based CDT has great potential …

Tumor immune escape is an important strategy of tumor survival. There are many
mechanisms of tumor immune escape, including immunosuppression, which has become a …

Genetic instability of tumor cells often leads to the occurrence of a large number of
mutations, and expression of non-synonymous mutations can produce tumor-specific …

Radiotherapy (RT), essential for treating various cancers, faces challenges from tumor
hypoxia, which induces radioresistance. A tumor‐targeted “prosthetic‐Arginine” …

An extensive body of literature describes anticancer property of dichloroacetate (DCA), but
its effective clinical administration in cancer therapy is still limited to clinical trials. The …

The immune system plays important roles in tumor development. According to the immune-
editing theory, immune escape is the key to tumor survival, and exploring the mechanisms of …

Abstract High-grade gliomas (HGGs), including glioblastoma and diffuse intrinsic pontine
glioma, are amongst the most fatal brain tumors. These tumors are associated with a dismal …