The past, present, and future of antibiotics

MA Cook, GD Wright - Science translational medicine, 2022 - science.org
Antibiotics have transformed modern medicine. They are essential for treating infectious
diseases and enable vital therapies and procedures. However, despite this success, their …

Emergent crisis of antibiotic resistance: A silent pandemic threat to 21st century

F Akram, M Imtiaz, I ul Haq - Microbial pathogenesis, 2023 - Elsevier
Antibiotic resistance has become an indispensably alarming menace to the global
community. The primary factors are overuse and abuse of antibiotics, lack of novel …

Various novel strategies for functionalization of gold and silver nanoparticles to hinder drug-resistant bacteria and cancer cells

M Alavi, R Kowalski, R Capasso… - Micro Nano Bio …, 2022 - mnba-journal.com
A higher reactivity of nanomaterials specifically inorganic nanoparticles (NPs) compared to
their counterparts, is caused by their unique physicochemical properties in the nanoscale …

REASSURED multiplex diagnostics: a critical review and forecast

JA Otoo, TS Schlappi - Biosensors, 2022 - mdpi.com
The diagnosis of infectious diseases is ineffective when the diagnostic test does not meet
one or more of the necessary standards of affordability, accessibility, and accuracy. The …

Advancements in antimicrobial nanoscale materials and self-assembling systems

JA Doolan, GT Williams, KLF Hilton… - Chemical Society …, 2022 - pubs.rsc.org
Antimicrobial resistance is directly responsible for more deaths per year than either
HIV/AIDS or malaria and is predicted to incur a cumulative societal financial burden of at …

Biological synthesis of nanostructured ZnO as a solar-light driven photocatalyst and antimicrobial agent

AA Sumra, M Aadil, SR Ejaz, S Anjum, T Saleem… - Ceramics …, 2022 - Elsevier
A good photocatalyst should have a high surface area, a substantial absorption capacity,
and a visible light active bandgap. Semi-conductive materials, particularly nanostructured …

Bacterial infections and cancer: exploring this association and its implications for cancer patients

K Yusuf, V Sampath, S Umar - International Journal of Molecular Sciences, 2023 - mdpi.com
Bacterial infections are common in the etiology of human diseases owing to the ubiquity of
bacteria. Such infections promote the development of periodontal disease, bacterial …

Healthcare as a driver, reservoir and amplifier of antimicrobial resistance: opportunities for interventions

D Cocker, G Birgand, N Zhu… - Nature Reviews …, 2024 - nature.com
Antimicrobial resistance (AMR) is a global health challenge that threatens humans, animals
and the environment. Evidence is emerging for a role of healthcare infrastructure …

Zinc oxide nanoparticles promise anticancer and antibacterial activity in ovarian cancer

AB Mousa, R Moawad, Y Abdallah… - Pharmaceutical …, 2023 - Springer
Background Ovarian cancer is the most lethal cancer in gynaecology. Surgery,
chemotherapy, and radiotherapy are the most often used cancer-fighting strategies. Post …

The scope of the antimicrobial resistance challenge

IN Okeke, MEA de Kraker, TP Van Boeckel, CK Kumar… - The Lancet, 2024 - thelancet.com
Summary Each year, an estimated 7· 7 million deaths are attributed to bacterial infections, of
which 4.95 million are associated with drug-resistant pathogens, and 1· 27 million are …