Diabetic wound-healing science

JL Burgess, WA Wyant, B Abdo Abujamra, RS Kirsner… - Medicina, 2021 - mdpi.com
Diabetes mellitus is an increasingly prevalent chronic metabolic disease characterized by
prolonged hyperglycemia that leads to long-term health consequences. It is estimated that …

Immunology of acute and chronic wound healing

K Raziyeva, Y Kim, Z Zharkinbekov, K Kassymbek… - Biomolecules, 2021 - mdpi.com
Skin wounds greatly affect the global healthcare system, creating a substantial burden on
the economy and society. Moreover, the situation is exacerbated by low healing rates, which …

Regulatory T cells in skin regeneration and wound healing

S Knoedler, L Knoedler, M Kauke-Navarro… - Military Medical …, 2023 - Springer
As the body's integumentary system, the skin is vulnerable to injuries. The subsequent
wound healing processes aim to restore dermal and epidermal integrity and functionality. To …

Instantly adhesive and ultra-elastic patches for dynamic organ and wound repair

P Chansoria, A Chaudhari, EL Etter… - Nature …, 2024 - nature.com
Bioadhesive materials and patches are promising alternatives to surgical sutures and
staples. However, many existing bioadhesives do not meet the functional requirements of …

Novel biotherapeutics targeting biomolecular and cellular approaches in diabetic wound healing

SK Singh, SD Dwivedi, K Yadav, K Shah, NS Chauhan… - Biomedicines, 2023 - mdpi.com
Wound healing responses play a major role in chronic inflammation, which affects millions of
people around the world. One of the daunting tasks of creating a wound-healing drug is …

Formononetin, a bioactive isoflavonoid constituent from Astragalus membranaceus (Fisch.) Bunge, ameliorates type 1 diabetes mellitus via activation of Keap1/Nrf2 …

H Chen, Y Lou, S Lin, X Tan, Y Zheng, H Yu… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Type 1 diabetes mellitus (T1DM) results from insulin
deficiency due to the destruction of pancreatic β-cells. Previously, our studies showed that …

Role of fibroblast plasticity and heterogeneity in modulating angiogenesis and healing in the diabetic foot ulcer

V Rai, R Moellmer, DK Agrawal - Molecular Biology Reports, 2023 - Springer
Chronic diabetic foot ulcers (DFUs) are an important clinical issue faced by clinicians
despite the advanced treatment strategies consisting of wound debridement, off-loading …

[HTML][HTML] Targeting members of the chemokine family as a novel approach to treating neuropathic pain

K Pawlik, J Mika - Molecules, 2023 - mdpi.com
Neuropathic pain is a debilitating condition that affects millions of people worldwide.
Numerous studies indicate that this type of pain is a chronic condition with a complex …

[HTML][HTML] Deciphering the crosstalk between inflammation and biofilm in chronic wound healing: Phytocompounds loaded bionanomaterials as therapeutics

S Sankar, GK Muthukaliannan - Saudi Journal of Biological Sciences, 2024 - Elsevier
In terms of the economics and public health, chronic wounds exert a significant detrimental
impact on the health care system. Bacterial infections, which cause the formation of highly …

A Schiff base hydrogel dressing loading extracts from Periplaneta Americana for diabetic wound healing

F Guo, Y Liu, S Chen, Y Lin, Y Yue - International Journal of Biological …, 2023 - Elsevier
As a common complication of diabetic patients, the chronic wound of diabetes has a high
incidence, expensive treatment, and recurrence probability, which causes long-term …