Cognitive decline in Parkinson disease

D Aarsland, B Creese, M Politis… - Nature Reviews …, 2017 - nature.com
Dementia is a frequent problem encountered in advanced stages of Parkinson disease (PD).
In recent years, research has focused on the pre-dementia stages of cognitive impairment in …

Are dementia with Lewy bodies and Parkinson's disease dementia the same disease?

KA Jellinger, AD Korczyn - Advances in Surgical and Medical …, 2023 - taylorfrancis.com
The clinical features of dementia with Lewy bodies (DLB) and Parkinson's disease dementia
(PDD) are similar and include dementia, cognitive fluctuations, and (visual) hallucinations in …

Visual dysfunction in Parkinson's disease

RS Weil, AE Schrag, JD Warren, SJ Crutch, AJ Lees… - Brain, 2016 - academic.oup.com
Patients with Parkinson's disease have a number of specific visual disturbances. These
include changes in colour vision and contrast sensitivity and difficulties with complex visual …

The role of noradrenaline in cognition and cognitive disorders

N Holland, TW Robbins, JB Rowe - Brain, 2021 - academic.oup.com
Many aspects of cognition and behaviour are regulated by noradrenergic projections to the
forebrain originating from the locus coeruleus, acting through alpha and beta …

Dementia with Lewy bodies and Parkinson's disease-dementia: current concepts and controversies

KA Jellinger - Journal of neural transmission, 2018 - Springer
Dementia with Lewy bodies (DLB) and Parkinson's disease-dementia (PDD), although
sharing many clinical, neurochemical and morphological features, according to DSM-5, are …

Parkinson's disease dementia: a neural networks perspective

J Gratwicke, M Jahanshahi, T Foltynie - Brain, 2015 - academic.oup.com
In the long-term, with progression of the illness, Parkinson's disease dementia affects up to
90% of patients with Parkinson's disease. With increasing life expectancy in western …

Cognition deficits in Parkinson's disease: mechanisms and treatment

C Fang, L Lv, S Mao, H Dong, B Liu - Parkinson's disease, 2020 - Wiley Online Library
Parkinson's disease (PD) is the second most common progressive neurodegenerative
disorder mainly in middle‐elderly population, which represents diverse nonmotor symptoms …

Genome‐wide association studies of cognitive and motor progression in Parkinson's disease

MMX Tan, MA Lawton, E Jabbari… - Movement …, 2021 - Wiley Online Library
Background There are currently no treatments that stop or slow the progression of
Parkinson's disease (PD). Case–control genome‐wide association studies have identified …

The clinical heterogeneity of Parkinson's disease and its therapeutic implications

JC Greenland, CH Williams‐Gray… - European Journal of …, 2019 - Wiley Online Library
Although Parkinson's disease (PD) is primarily a movement disorder, there are a range of
associated nonmotor symptoms, including cognitive impairment, depression and sleep …

[HTML][HTML] The role of dopamine in the brain-lessons learned from Parkinson's disease

D Meder, DM Herz, JB Rowe, S Lehéricy, HR Siebner - Neuroimage, 2019 - Elsevier
Parkinson's disease causes a characteristic combination of motor symptoms due to
progressive neurodegeneration of dopaminergic neurons in the substantia nigra pars …