COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection

WY Chi, YD Li, HC Huang, TEH Chan, SY Chow… - Journal of biomedical …, 2022 - Springer
Abstract Coronavirus Disease 2019 (COVID-19) has been the most severe public health
challenge in this century. Two years after its emergence, the rapid development and …

Molecular mechanism of interaction between SARS-CoV-2 and host cells and interventional therapy

Q Zhang, R ** neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology
L Piccoli, YJ Park, MA Tortorici, N Czudnochowski… - Cell, 2020 - cell.com
Analysis of the specificity and kinetics of neutralizing antibodies (nAbs) elicited by SARS-
CoV-2 infection is crucial for understanding immune protection and identifying targets for …

The SARS-CoV-2 monoclonal antibody combination, AZD7442, is protective in nonhuman primates and has an extended half-life in humans

YM Loo, PM McTamney, RH Arends… - Science translational …, 2022 - science.org
Despite the success of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
vaccines, there remains a need for more prevention and treatment options for individuals …

Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion

DJ Benton, AG Wrobel, P Xu, C Roustan, SR Martin… - Nature, 2020 - nature.com
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is initiated by
virus binding to the ACE2 cell-surface receptors,,–, followed by fusion of the virus and cell …

[HTML][HTML] SARS-CoV-2 infection depends on cellular heparan sulfate and ACE2

TM Clausen, DR Sandoval, CB Spliid, J Pihl… - Cell, 2020 - cell.com
We show that SARS-CoV-2 spike protein interacts with both cellular heparan sulfate and
angiotensin-converting enzyme 2 (ACE2) through its receptor-binding domain (RBD) …

Sequence analysis of the emerging SARS‐CoV‐2 variant Omicron in South Africa

L Wang, G Cheng - Journal of medical virology, 2022 - Wiley Online Library
Despite the worldwide vaccination, the COVID‐19 pandemic continues as SARS‐CoV‐2
evolves into numerous variants. Since the first identification of the novel SARS‐CoV‐2 …