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The role of AUTS2 in neurodevelopment and human evolution
The autism susceptibility candidate 2 (AUTS2) gene is associated with multiple neurological
diseases, including autism, and has been implicated as an important gene in human …
diseases, including autism, and has been implicated as an important gene in human …
Language deficits in schizophrenia and autism as related oscillatory connectomopathies: an evolutionary account
Schizophrenia (SZ) and autism spectrum disorders (ASD) are characterised by marked
language deficits, but it is not clear how these arise from gene mutations associated with the …
language deficits, but it is not clear how these arise from gene mutations associated with the …
Genome-wide association study reveals two new risk loci for bipolar disorder
TW Mühleisen, M Leber, TG Schulze… - Nature …, 2014 - nature.com
Bipolar disorder (BD) is a common and highly heritable mental illness and genome-wide
association studies (GWAS) have robustly identified the first common genetic variants …
association studies (GWAS) have robustly identified the first common genetic variants …
Life extension factor klotho enhances cognition
Aging is the primary risk factor for cognitive decline, an emerging health threat to aging
societies worldwide. Whether anti-aging factors such as klotho can counteract cognitive …
societies worldwide. Whether anti-aging factors such as klotho can counteract cognitive …
Cohort profile: the Lothian Birth Cohorts of 1921 and 1936
This cohort profile describes the origins, tracing, recruitment, testing and follow-up of the
University of Edinburgh-based Lothian Birth Cohorts of 1921 (LBC1921; N= 550) and 1936 …
University of Edinburgh-based Lothian Birth Cohorts of 1921 (LBC1921; N= 550) and 1936 …
GWAS for executive function and processing speed suggests involvement of the CADM2 gene
CA Ibrahim-Verbaas, J Bressler, S Debette… - Molecular …, 2016 - nature.com
To identify common variants contributing to normal variation in two specific domains of
cognitive functioning, we conducted a genome-wide association study (GWAS) of executive …
cognitive functioning, we conducted a genome-wide association study (GWAS) of executive …
Function and Regulation of AUTS2, a Gene Implicated in Autism and Human Evolution
Nucleotide changes in the AUTS2 locus, some of which affect only noncoding regions, are
associated with autism and other neurological disorders, including attention deficit …
associated with autism and other neurological disorders, including attention deficit …
Genome-wide association study of toxic metals and trace elements reveals novel associations
E Ng, PM Lind, C Lindgren, E Ingelsson… - Human molecular …, 2015 - academic.oup.com
The accumulation of toxic metals in the human body is influenced by exposure and
mechanisms involved in metabolism, some of which may be under genetic control. This is …
mechanisms involved in metabolism, some of which may be under genetic control. This is …
Susceptibility of brain atrophy to TRIB3 in Alzheimer's disease, evidence from functional prioritization in imaging genetics
The joint modeling of brain imaging information and genetic data is a promising research
avenue to highlight the functional role of genes in determining the pathophysiological …
avenue to highlight the functional role of genes in determining the pathophysiological …
Category fluency, latent semantic analysis and schizophrenia: a candidate gene approach
KK Nicodemus, B Elvevåg, PW Foltz, M Rosenstein… - Cortex, 2014 - Elsevier
Background Category fluency is a widely used task that relies on multiple neurocognitive
processes and is a sensitive assay of cortical dysfunction, including in schizophrenia. The …
processes and is a sensitive assay of cortical dysfunction, including in schizophrenia. The …