The role of AUTS2 in neurodevelopment and human evolution

N Oksenberg, N Ahituv - Trends in Genetics, 2013 - cell.com
The autism susceptibility candidate 2 (AUTS2) gene is associated with multiple neurological
diseases, including autism, and has been implicated as an important gene in human …

Language deficits in schizophrenia and autism as related oscillatory connectomopathies: an evolutionary account

E Murphy, A Benítez-Burraco - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
Schizophrenia (SZ) and autism spectrum disorders (ASD) are characterised by marked
language deficits, but it is not clear how these arise from gene mutations associated with the …

Genome-wide association study reveals two new risk loci for bipolar disorder

TW Mühleisen, M Leber, TG Schulze… - Nature …, 2014 - nature.com
Bipolar disorder (BD) is a common and highly heritable mental illness and genome-wide
association studies (GWAS) have robustly identified the first common genetic variants …

Life extension factor klotho enhances cognition

DB Dubal, JS Yokoyama, L Zhu, L Broestl, K Worden… - Cell reports, 2014 - cell.com
Aging is the primary risk factor for cognitive decline, an emerging health threat to aging
societies worldwide. Whether anti-aging factors such as klotho can counteract cognitive …

Cohort profile: the Lothian Birth Cohorts of 1921 and 1936

IJ Deary, AJ Gow, A Pattie… - International journal of …, 2012 - academic.oup.com
This cohort profile describes the origins, tracing, recruitment, testing and follow-up of the
University of Edinburgh-based Lothian Birth Cohorts of 1921 (LBC1921; N= 550) and 1936 …

GWAS for executive function and processing speed suggests involvement of the CADM2 gene

CA Ibrahim-Verbaas, J Bressler, S Debette… - Molecular …, 2016 - nature.com
To identify common variants contributing to normal variation in two specific domains of
cognitive functioning, we conducted a genome-wide association study (GWAS) of executive …

Function and Regulation of AUTS2, a Gene Implicated in Autism and Human Evolution

N Oksenberg, L Stevison, JD Wall, N Ahituv - PLoS genetics, 2013 - journals.plos.org
Nucleotide changes in the AUTS2 locus, some of which affect only noncoding regions, are
associated with autism and other neurological disorders, including attention deficit …

Genome-wide association study of toxic metals and trace elements reveals novel associations

E Ng, PM Lind, C Lindgren, E Ingelsson… - Human molecular …, 2015 - academic.oup.com
The accumulation of toxic metals in the human body is influenced by exposure and
mechanisms involved in metabolism, some of which may be under genetic control. This is …

Susceptibility of brain atrophy to TRIB3 in Alzheimer's disease, evidence from functional prioritization in imaging genetics

M Lorenzi, A Altmann, B Gutman, S Wray… - Proceedings of the …, 2018 - pnas.org
The joint modeling of brain imaging information and genetic data is a promising research
avenue to highlight the functional role of genes in determining the pathophysiological …

Category fluency, latent semantic analysis and schizophrenia: a candidate gene approach

KK Nicodemus, B Elvevåg, PW Foltz, M Rosenstein… - Cortex, 2014 - Elsevier
Background Category fluency is a widely used task that relies on multiple neurocognitive
processes and is a sensitive assay of cortical dysfunction, including in schizophrenia. The …