Cell morphology encodes essential information on many underlying biological processes. It
is commonly used by clinicians and researchers in the study, diagnosis, prognosis, and …

The cytoskeleton architecture supports many cellular functions. Cytoskeleton networks form
complex intracellular structures that vary during the cell cycle and between different cell …

Focal adhesions are large protein complexes organized at the basal surface of cells, which
physically connect the extracellular matrix to the cytoskeleton and have long been …

The nucleus has long been postulated to play a critical physical role during cell polarization
and migration, but that role has not been defined or rigorously tested. Here, we enucleated …

Simple Summary Tumor Treating Fields (TTFields), encompassing alternating electric fields
within the intermediate frequency range, is an anticancer treatment delivered to the tumor …

Cells often migrate in vivo in an extracellular matrix that is intrinsically three-dimensional
(3D) and the role of actin filament architecture in 3D cell migration is less well understood …

Eukaryotic cells alternate between episodes of fast and persistent movements and
“hesitation” episodes of low speed and low persistence. Unlike the well-understood tumbling …

Cells are equipped with asymmetrically localised and functionally specialised components,
including cytoskeletal structures and organelles. Positioning these components to specific …

Microtubule and actin are the two major cytoskeletal polymers that form organized functional
structures in the interior of eukaryotic cells. Although the structural mechanics of the …

Ageing research has focused either on assessing organ-and tissue-based changes, such as
lung capacity and cardiac function, or on changes at the molecular scale such as gene …