Prenylation is a class of lipid modification involving covalent addition of either farnesyl (15-
carbon) or geranylgeranyl (20-carbon) isoprenoids to conserved cysteine residues at or …

GTPases of the Ras superfamily regulate many aspects of cell growth, differentiation and
action. Their functions depend on their ability to alternate between inactive and active forms …

The “Gold Standard” in Biochemistry text books. Biochemistry 4e, is a modern classic that
has been thoroughly revised. Don and Judy Voet explain biochemical concepts while …

A wealth of protein and DNA sequence data is being generated by genome projects and
other sequencing efforts. A crucial barrier to deciphering these sequences and …

Embryonic development in many angiosperms occurs concomitantly with the development
of the ovary into a specialized organ, the fruit, which provides a suitable environment for …

The yeast cell wall is a strong, but elastic, structure that is essential not only for the
maintenance of cell shape and integrity, but also for progression through the cell cycle …

The modification of eukaryotic proteins by isoprenoid lipids, which is known as prenylation,
controls the localization and activity of a range of proteins that have crucial functions in …

The yeast cell wall is a highly dynamic structure that is responsible for protecting the cell
from rapid changes in external osmotic potential. The wall is also critical for cell expansion …

The goal of an activity-directed isolation process is to isolate bioactive compounds which
may provide structural leads of therapeutic importance. Whereas the traditional process of …

Palmitate modifies both peripheral and integral membrane proteins and its addition can be
permanent or transient, which makes it unique among the lipid modifications of proteins. The …