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Prebiotic peptides: Molecular hubs in the origin of life
The fundamental roles that peptides and proteins play in today's biology makes it almost
indisputable that peptides were key players in the origin of life. Insofar as it is appropriate to …
indisputable that peptides were key players in the origin of life. Insofar as it is appropriate to …
Strecker reaction and α-amino nitriles: Recent advances in their chemistry, synthesis, and biological properties
Abstract α-Amino nitrile compounds have a profound impact on bio-chemical sciences, as
they have been prepared from inexpensive starting materials and have become valuable …
they have been prepared from inexpensive starting materials and have become valuable …
Ester‐mediated amide bond formation driven by wet–dry cycles: A possible path to polypeptides on the prebiotic earth
Although it is generally accepted that amino acids were present on the prebiotic Earth, the
mechanism by which α‐amino acids were condensed into polypeptides before the …
mechanism by which α‐amino acids were condensed into polypeptides before the …
[کتاب][B] The emergence of life: from chemical origins to synthetic biology
PL Luisi - 2016 - books.google.com
Addressing the emergence of life from a systems biology perspective, this new edition has
undergone extensive revision, reflecting changes in scientific understanding and evolution …
undergone extensive revision, reflecting changes in scientific understanding and evolution …
Formation of oligopeptides in high yield under simple programmable conditions
Many high-yielding reactions for forming peptide bonds have been developed but these are
complex, requiring activated amino-acid precursors and heterogeneous supports. Herein we …
complex, requiring activated amino-acid precursors and heterogeneous supports. Herein we …
Selective incorporation of proteinaceous over nonproteinaceous cationic amino acids in model prebiotic oligomerization reactions
Numerous long-standing questions in origins-of-life research center on the history of
biopolymers. For example, how and why did nature select the polypeptide backbone and …
biopolymers. For example, how and why did nature select the polypeptide backbone and …
Protocellular Heme and Iron–Sulfur Clusters
Conspectus Central to the quest of understanding the emergence of life is to uncover the
role of metals, particularly iron, in sha** prebiotic chemistry. Iron, as the most abundant of …
role of metals, particularly iron, in sha** prebiotic chemistry. Iron, as the most abundant of …
Phosphorylation on the early earth
Phosphorus is an element critical to the formation of several biomolecules, including nucleic
acids, the energy transfer molecule ATP, and phospholipids. It hence lies at the heart of …
acids, the energy transfer molecule ATP, and phospholipids. It hence lies at the heart of …
Amyloid and the origin of life: self-replicating catalytic amyloids as prebiotic informational and protometabolic entities
CPJ Maury - Cellular and Molecular Life Sciences, 2018 - Springer
A crucial stage in the origin of life was the emergence of the first molecular entity that was
able to replicate, transmit information, and evolve on the early Earth. The amyloid world …
able to replicate, transmit information, and evolve on the early Earth. The amyloid world …
Setting the geological scene for the origin of life and continuing open questions about its emergence
The origin of life is one of the most fundamental questions of humanity. It has been and is
still being addressed by a wide range of researchers from different fields, with different …
still being addressed by a wide range of researchers from different fields, with different …