Prenatal developmental origins of behavior and mental health: The influence of maternal stress in pregnancy

BRH Van den Bergh, MI van den Heuvel… - Neuroscience & …, 2020 - Elsevier
Accumulating research shows that prenatal exposure to maternal stress increases the risk
for behavioral and mental health problems later in life. This review systematically analyzes …

Inflammation in psychiatric disorders: what comes first?

ME Bauer, AL Teixeira - Annals of the New York Academy of …, 2019 - Wiley Online Library
Neuropsychiatric disorders (ie, mood disorders and schizophrenia) and inflammation are
closely intertwined, and possibly powering each other in a bidirectional loop. Depression …

Transferring the blues: depression-associated gut microbiota induces neurobehavioural changes in the rat

JR Kelly, Y Borre, C O'Brien, E Patterson… - Journal of psychiatric …, 2016 - Elsevier
The gut microbiota interacts with the host via neuroimmune, neuroendocrine and neural
pathways. These pathways are components of the brain-gut-microbiota axis and preclinical …

[HTML][HTML] Health relevance of the modification of low grade inflammation in ageing (inflammageing) and the role of nutrition

PC Calder, N Bosco, R Bourdet-Sicard, L Capuron… - Ageing research …, 2017 - Elsevier
Ageing of the global population has become a public health concern with an important socio-
economic dimension. Ageing is characterized by an increase in the concentration of …

Antidepressant activity of anti-cytokine treatment: a systematic review and meta-analysis of clinical trials of chronic inflammatory conditions

N Kappelmann, G Lewis, R Dantzer, PB Jones… - Molecular …, 2018 - nature.com
Inflammatory cytokines are commonly elevated in acute depression and are associated with
resistance to monoaminergic treatment. To examine the potential role of cytokines in the …

Cortisol and major depressive disorder—translating findings from humans to animal models and back

LS Nandam, M Brazel, M Zhou, DJ Jhaveri - Frontiers in psychiatry, 2020 - frontiersin.org
Major depressive disorder (MDD) is a global problem for which current pharmacotherapies
are not completely effective. Hypothalamic–pituitary–adrenal (HPA) axis dysfunction has …

Peripheral cytokine levels across psychiatric disorders: A systematic review and network meta-analysis

Y Zhang, J Wang, Y Ye, Y Zou, W Chen, Z Wang… - Progress in Neuro …, 2023 - Elsevier
Immune dysregulated cytokine production is involved in mental diseases. However, the
results are inconsistent and the pattern of cytokine alterations has not been compared …

Comorbidity between post-traumatic stress disorder and major depressive disorder: alternative explanations and treatment considerations

JD Flory, R Yehuda - Dialogues in clinical neuroscience, 2015 - Taylor & Francis
Approximately half of people with post-traumatic stress disorder (PTSD) also suffer from
Major Depressive Disorder (MDD). The current paper examines evidence for two …

[HTML][HTML] Why are depressed patients inflamed? A reflection on 20 years of research on depression, glucocorticoid resistance and inflammation

CM Pariante - European neuropsychopharmacology, 2017 - Elsevier
Studies over the last 20 years have demonstrated that increased inflammation and
hyperactivity of the hypothalamic–pituitary–adrenal (HPA) axis are two of the most consistent …

Is the HPA axis as target for depression outdated, or is there a new hope?

A Menke - Frontiers in psychiatry, 2019 - frontiersin.org
Major depressive disorder (MDD) is a very common stress-related mental disorder that
carries a huge burden for affected patients and the society. It is associated with a high …