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Peptide–drug conjugates as effective prodrug strategies for targeted delivery
Peptide–drug conjugates (PDCs) represent an important class of therapeutic agents that
combine one or more drug molecules with a short peptide through a biodegradable linker …
combine one or more drug molecules with a short peptide through a biodegradable linker …
Self-assembled peptide nanostructures for functional materials
Nature is an important inspirational source for scientists, and presents complex and elegant
examples of adaptive and intelligent systems created by self-assembly. Significant effort has …
examples of adaptive and intelligent systems created by self-assembly. Significant effort has …
Ratiometric and colorimetric fluorescent probe for hypochlorite monitor and application for bioimaging in living cells, bacteria and zebrafish
X He, H Chen, C Xu, J Fan, W Xu, Y Li, H Deng… - Journal of hazardous …, 2020 - Elsevier
Abstract Hypochlorous acid (HOCl)/hypochlorite (ClO−) was a biologically important
component of reactive oxygen species (ROS) and plays a key role in human immune …
component of reactive oxygen species (ROS) and plays a key role in human immune …
Alkaline phosphatase-triggered simultaneous hydrogelation and chemiluminescence
Z Hai, J Li, J Wu, J Xu, G Liang - Journal of the American Chemical …, 2017 - ACS Publications
Chemiluminescence (CL) has a higher signal-to-noise ratio than fluorescence, but the use of
CL to track an enzyme-instructed self-assembly (EISA) process has not been reported. In …
CL to track an enzyme-instructed self-assembly (EISA) process has not been reported. In …
A naphthalimide-based chemodosimetric probe for ratiometric detection of hydrazine
Y Hao, Y Zhang, K Ruan, W Chen, B Zhou… - Sensors and Actuators B …, 2017 - Elsevier
A new naphthalimide-based probe was designed and synthesized for the rationmetric
detection of hydrazine. The probe is designed in such a way that the intramolecular charge …
detection of hydrazine. The probe is designed in such a way that the intramolecular charge …
Optimized Two-Photon Imaging by Stimuli-Responsive Peptide Self-Assembly Facilitates Self-Assisted Counteraction of Cisplatin-Resistance in Cancer Cells
Accurate diagnosis and effective treatment of tumors remain significant clinical challenges.
While fluorescence imaging is essential for tumor detection, it has limitations in terms of …
While fluorescence imaging is essential for tumor detection, it has limitations in terms of …
Detection of misdistribution of tyrosinase from melanosomes to lysosomes and its upregulation under psoralen/ultraviolet a with a melanosome-targeting tyrosinase …
Tyrosinase is regarded as an important biomarker of melanoma cancer, and its metabolism
is closely related to some severe skin diseases such as vitiligo. Since tyrosinase is mainly …
is closely related to some severe skin diseases such as vitiligo. Since tyrosinase is mainly …
MicroRNA detection with turnover amplification via hybridization-mediated staudinger reduction for pancreatic cancer diagnosis
L **an, F Xu, J Liu, N Xu, H Li, H Ge… - Journal of the …, 2019 - ACS Publications
The occurrence of and development in the early pathological stage of pancreatic cancer has
proved to be associated with microRNAs. However, it remains a great challenge to directly …
proved to be associated with microRNAs. However, it remains a great challenge to directly …
Smart self-assembled organic nanoprobe for protein-specific detection: design, synthesis, application, and mechanism studies
Specific detection or imaging protein has high potential to contribute greatly to medical
diagnosis, biological research, and therapeutic applications. The level of human serum …
diagnosis, biological research, and therapeutic applications. The level of human serum …
Near-infrared mito-specific fluorescent probe for ratiometric detection and imaging of alkaline phosphatase activity with high sensitivity
Q Zhang, S Li, C Fu, Y **ao, P Zhang… - Journal of Materials …, 2019 - pubs.rsc.org
Fluorescent probe-based analytical methods for biological species have gained increasing
attention for their powerful detection and imaging capabilities. However, it is still …
attention for their powerful detection and imaging capabilities. However, it is still …