Azoreductase: a key player of xenobiotic metabolism

SA Misal, KR Gawai - Bioresources and Bioprocessing, 2018 - Springer
Azoreductases are diverse flavoenzymes widely present among microorganisms and higher
eukaryotes. They are mainly involved in the biotransformation and detoxification of azo dyes …

The FMN-dependent two-component monooxygenase systems

HR Ellis - Archives of biochemistry and biophysics, 2010 - Elsevier
The FMN-dependent two-component monooxygenase systems catalyze a diverse range of
reactions. These two-component systems are composed of an FMN reductase enzyme and …

Taxonomic and functional characterization of a microbial community from a volcanic englacial ecosystem in Deception Island, Antarctica

E Martinez-Alonso, S Pena-Perez, S Serrano… - Scientific reports, 2019 - nature.com
Glaciers are populated by a large number of microorganisms including bacteria, archaea
and microeukaryotes. Several factors such as solar radiation, nutrient availability and water …

Removal effectiveness and mechanisms of naphthalene and heavy metals from artificially contaminated soil by iron chelate-activated persulfate

DYS Yan, IMC Lo - Environmental Pollution, 2013 - Elsevier
The effectiveness and mechanisms of naphthalene and metal removal from artificially
contaminated soil by FeEDTA/FeEDDS-activated persulfate were investigated through batch …

Reducing alcohol levels in wines through rational and evolutionary engineering of Saccharomyces cerevisiae

V Tilloy, A Cadière, M Ehsani, S Dequin - International journal of food …, 2015 - Elsevier
Over the past two decades, the level of ethanol in wine has increased in most wine-
producing regions, raising a number of issues related to consumer health, prevention …

Characterization of chlorophenol 4-monooxygenase (TftD) and NADH: FAD oxidoreductase (TftC) of Burkholderia cepacia AC1100

BN Webb, JW Ballinger, E Kim, SM Belchik… - Journal of Biological …, 2010 - ASBMB
Burkholderia cepacia AC1100 completely degrades 2, 4, 5-trichlorophenol, in which an
FADH 2-dependent monooxygenase (TftD) and an NADH: FAD oxidoreductase (TftC) …

Mechanism for sulfur acquisition by the alkanesulfonate monooxygenase system

HR Ellis - Bioorganic Chemistry, 2011 - Elsevier
The bacterial alkanesulfonate monooxygenase system is involved in the acquisition of sulfur
from organosulfonated compounds during limiting sulfur conditions. The reaction relies on …

Assembly of a π–π stack of ligands in the binding site of an acetylcholine-binding protein

M Stornaiuolo, GE De Kloe, P Rucktooa, A Fish… - Nature …, 2013 - nature.com
Acetylcholine-binding protein is a water-soluble homologue of the extracellular ligand-
binding domain of cys-loop receptors. It is used as a structurally accessible prototype for …

Reaction mechanism of azoreductases suggests convergent evolution with quinone oxidoreductases

A Ryan, CJ Wang, N Laurieri, I Westwood, E Sim - Protein & cell, 2010 - Springer
Azoreductases are involved in the bioremediation by bacteria of azo dyes found in waste
water. In the gut flora, they activate azo pro-drugs, which are used for treatment of …

A novel mechanism for azoreduction

A Ryan, N Laurieri, I Westwood, CJ Wang… - Journal of molecular …, 2010 - Elsevier
Azoreductases are important due to their ability to activate anti-inflammatory azo pro-drugs
and to detoxify azo dyes. Three genes encoding azoreductases have been identified in …