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Diminazene Aceturate, an angiotensin converting enzyme 2 (ACE2) activator, promotes cardioprotection in ischemia/reperfusion-induced cardiac injury
This study aimed to investigate whether the Diminazene Aceturate (DIZE), an angiotensin-
converting enzyme 2 (ACE2) activator, can revert cardiac dysfunction in ischemia …
converting enzyme 2 (ACE2) activator, can revert cardiac dysfunction in ischemia …
Mortality rate and predictors of COVID-19 inpatients in Ethiopia: a systematic review and meta-analysis
Introduction The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an
extremely rare virus that devastates the economy and claims human lives. Despite countries' …
extremely rare virus that devastates the economy and claims human lives. Despite countries' …
Complication and sequelae of COVID-19: what should we pay attention to in the post-epidemic era
K Yang, G Wen, J Wang, S Zhou, W Da… - Frontiers in …, 2021 - frontiersin.org
COVID-19 is widespread worldwide and seriously affects the daily life and health of humans.
Countries around the world are taking necessary measures to curb the spread. However …
Countries around the world are taking necessary measures to curb the spread. However …
Pharmacological potential of new metronidazole/eugenol/dihydroeugenol hybrids against Trypanosoma cruzi in vitro and in vivo
E Gonçalves-Santos, IS Caldas, VÂ Fernandes… - International …, 2023 - Elsevier
Aims From well-delimited immunomodulatory, redox and antimicrobial properties;
metronidazole and eugenol were used as structural platforms to assembly two new …
metronidazole and eugenol were used as structural platforms to assembly two new …
Oxidative stress, cardiomyocytes premature senescence and contractile dysfunction in in vitro and in vivo experimental models of Chagas disease
SS Nogueira, MA Souza, EC Santos, IS Caldas… - Acta Tropica, 2023 - Elsevier
Aims The relationship between redox imbalance and cardiovascular senescence in
infectious myocarditis is unknown. Thus, the aim of this study was to investigate whether …
infectious myocarditis is unknown. Thus, the aim of this study was to investigate whether …
Identification of host antioxidant effectors as thioridazine targets: Impact on cardiomyocytes infection and Trypanosoma cruzi-induced acute myocarditis
ELBC Domingues, E Gonçalves-Santos… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Phenothiazines inhibit antioxidant enzymes in trypanosomatids. However, potential
interferences with host cell antioxidant defenses are central concerns in using these drugs to …
interferences with host cell antioxidant defenses are central concerns in using these drugs to …
Chronic rapamycin pretreatment modulates arginase/inducible nitric oxide synthase balance attenuating aging-dependent susceptibility to Trypanosoma cruzi …
M Pereira-Santos, E Gonçalves-Santos… - Experimental …, 2022 - Elsevier
Considering the efficacy of rapamycin in increasing lifespan and healthspan, attenuating the
aging-dependent immunological decline, we compared the evolution of Trypanosoma cruzi …
aging-dependent immunological decline, we compared the evolution of Trypanosoma cruzi …
Resistance Exercise and Whey protein supplementation reduce mechanical Allodynia and spinal microglia activation after Acute muscle trauma in rats
Muscle injury caused by direct trauma to the skeletal muscle is among the main
musculoskeletal disorders. Non-pharmacological treatments have been effective in …
musculoskeletal disorders. Non-pharmacological treatments have been effective in …