Oxygen–Ozone therapy in the rehabilitation field: state of the art on mechanisms of action, safety andeffectiveness in patients with musculoskeletal disorders
In recent years, the interest in oxygen–ozone (O2O3) therapy application has considerably
increased in the field of rehabilitation. Despite its widespread use in common clinical …
increased in the field of rehabilitation. Despite its widespread use in common clinical …
From pathogenesis to therapy in knee osteoarthritis: bench-to-bedside
Osteoarthritis (OA) is currently the most widespread musculoskeletal condition and primarily
affects weight-bearing joints such as the knees and hips. Importantly, knee OA remains a …
affects weight-bearing joints such as the knees and hips. Importantly, knee OA remains a …
Cell-free osteoarthritis treatment with sustained-release of chondrocyte-targeting exosomes from umbilical cord-derived mesenchymal stem cells to rejuvenate aging …
H Cao, M Chen, X Cui, Y Liu, Y Liu, S Deng, T Yuan… - ACS …, 2023 - ACS Publications
As chondrocytes from osteoarthritic cartilage usually exhibit aging and senescent
characteristics, targeting aging chondrocytes could be a potential therapeutic strategy. In this …
characteristics, targeting aging chondrocytes could be a potential therapeutic strategy. In this …
Treatment of knee osteoarthritis with intra-articular injection of allogeneic adipose-derived stem cells (ADSCs) ELIXCYTE®: a phase I/II, randomized, active-control …
CF Chen, CC Hu, CT Wu, HTH Wu, CS Chang… - Stem Cell Research & …, 2021 - Springer
Objective To evaluate the safety and efficacy of intra-articular (IA) injection of allogeneic
adipose-derived stem cells (ADSCs) ELIXCYTE® for knee osteoarthritis. Methods This was …
adipose-derived stem cells (ADSCs) ELIXCYTE® for knee osteoarthritis. Methods This was …
Cathepsin K in pathological conditions and new therapeutic and diagnostic perspectives
O Mijanović, A Jakovleva, A Branković… - International journal of …, 2022 - mdpi.com
Cathepsin K (CatK) is a part of the family of cysteine proteases involved in many important
processes, including the degradation activity of collagen 1 and elastin in bone resorption …
processes, including the degradation activity of collagen 1 and elastin in bone resorption …
Stromal vascular fraction therapy for knee osteoarthritis: a systematic review
A Boada-Pladellorens, M Avellanet… - Therapeutic …, 2022 - journals.sagepub.com
Background: Regenerative cell therapies, such as adipose-derived stromal vascular fraction
(SVF), have been postulated as potential treatments for knee osteoarthritis (KOA) …
(SVF), have been postulated as potential treatments for knee osteoarthritis (KOA) …
Hyaluronic acid in rheumatology
H Sprott, C Fleck - Pharmaceutics, 2023 - mdpi.com
Hyaluronic acid (HA), also known as hyaluronan, is an anionic glycosaminoglycan widely
distributed throughout various tissues of the human body. It stands out from other …
distributed throughout various tissues of the human body. It stands out from other …
Chondrotoxicity of intra-articular injection treatment: a sco** review
C Pirri, A Sorbino, N Manocchio, N Pirri… - International Journal of …, 2024 - mdpi.com
The purpose of this sco** review was to identify possible chondrotoxic effects caused by
drugs usually used for intra-articular injections. PubMed, Scopus, Web of Science and …
drugs usually used for intra-articular injections. PubMed, Scopus, Web of Science and …
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Early osteoarthritis (EOA) still represents a challenge for clinicians. Although there is no
consensus on its definition and diagnosis, a prompt therapeutic intervention in the early …
consensus on its definition and diagnosis, a prompt therapeutic intervention in the early …