The schizophrenia syndrome, circa 2024: What we know and how that informs its nature
R Tandon, H Nasrallah, S Akbarian… - Schizophrenia …, 2024 - Elsevier
With new data about different aspects of schizophrenia being continually generated, it
becomes necessary to periodically revisit exactly what we know. Along with a need to review …
becomes necessary to periodically revisit exactly what we know. Along with a need to review …
Bringing Imaging Biomarkers Into Clinical Reality in Psychiatry
A Etkin, DH Mathalon - JAMA psychiatry, 2024 - jamanetwork.com
Importance Advancing precision psychiatry, where treatments are based on an individual's
biology rather than solely their clinical presentation, requires attention to several key …
biology rather than solely their clinical presentation, requires attention to several key …
Development of the PSYCHS: Positive SYmptoms and Diagnostic Criteria for the CAARMS Harmonized with the SIPS
SW Woods, S Parker, MJ Kerr, BC Walsh… - Early Intervention in …, 2024 - Wiley Online Library
Aim To harmonize two ascertainment and severity rating instruments commonly used for the
clinical high risk syndrome for psychosis (CHR‐P): the Structured Interview for Psychosis …
clinical high risk syndrome for psychosis (CHR‐P): the Structured Interview for Psychosis …
Normative modeling of brain morphometry in clinical high risk for psychosis
Importance The lack of robust neuroanatomical markers of psychosis risk has been
traditionally attributed to heterogeneity. A complementary hypothesis is that variation in …
traditionally attributed to heterogeneity. A complementary hypothesis is that variation in …
Improving prediction of psychosis in youth at clinical high-risk: pre-baseline symptom duration and cortical thinning as moderators of the NAPLS2 risk calculator
MA Worthington, MA Collins, J Addington… - Psychological …, 2024 - cambridge.org
BackgroundClinical implementation of risk calculator models in the clinical high-risk for
psychosis (CHR-P) population has been hindered by heterogeneous risk distributions …
psychosis (CHR-P) population has been hindered by heterogeneous risk distributions …
Accelerating medicines partnership® Schizophrenia (AMP® SCZ): Rationale and study design of the largest global prospective cohort study of clinical high risk for …
This article describes the rationale, aims, and methodology of the Accelerating Medicines
Partnership® Schizophrenia (AMP® SCZ). This is the largest international collaboration to …
Partnership® Schizophrenia (AMP® SCZ). This is the largest international collaboration to …
Relations of lifetime perceived stress and basal cortisol with hippocampal volume among healthy adolescents and those at clinical high risk for psychosis: A structural …
Background Hippocampal volume (HV) is sensitive to environmental influences. Under
normative conditions in humans, HV increases linearly into childhood and asymptotes in …
normative conditions in humans, HV increases linearly into childhood and asymptotes in …
RETRACTED: Dynamic Prediction of Outcomes for Youth at Clinical High Risk for Psychosis: A Joint Modeling Approach
Importance Leveraging the dynamic nature of clinical variables in the clinical high risk for
psychosis (CHR-P) population has the potential to significantly improve the performance of …
psychosis (CHR-P) population has the potential to significantly improve the performance of …
Recent updates on predicting conversion in youth at clinical high risk for psychosis
N Caballero, S Machiraju, A Diomino… - Current Psychiatry …, 2023 - Springer
Abstract Purpose of Review This review highlights recent advances in the prediction and
treatment of psychotic conversion. Over the past 25 years, research into the prodromal …
treatment of psychotic conversion. Over the past 25 years, research into the prodromal …
Rethinking the first episode of schizophrenia: identifying convergent mechanisms during development and moving toward prediction
The neurodevelopmental hypothesis of schizophrenia has long suggested that the cardinal
psychotic symptoms that have traditionally defined the disorder, and which most commonly …
psychotic symptoms that have traditionally defined the disorder, and which most commonly …