Long non-coding RNAs: definitions, functions, challenges and recommendations
Genes specifying long non-coding RNAs (lncRNAs) occupy a large fraction of the genomes
of complex organisms. The term 'lncRNAs' encompasses RNA polymerase I (Pol I), Pol II …
of complex organisms. The term 'lncRNAs' encompasses RNA polymerase I (Pol I), Pol II …
Role of pyroptosis in inflammation and cancer
X Wei, F **e, X Zhou, Y Wu, H Yan, T Liu… - Cellular & molecular …, 2022 - nature.com
Pyroptosis is a form of programmed cell death mediated by gasdermin and is a product of
continuous cell expansion until the cytomembrane ruptures, resulting in the release of …
continuous cell expansion until the cytomembrane ruptures, resulting in the release of …
Integrated lncRNA function upon genomic and epigenomic regulation
Although some long noncoding (lnc) RNAs are known since the 1950s, the past 25 years
have uncovered myriad lncRNAs with diverse sequences, structures, and functions. The …
have uncovered myriad lncRNAs with diverse sequences, structures, and functions. The …
LNCcation: lncRNA localization and function
Subcellular localization of RNAs has gained attention in recent years as a prevalent
phenomenon that influences numerous cellular processes. This is also evident for the large …
phenomenon that influences numerous cellular processes. This is also evident for the large …
[HTML][HTML] Gene regulation by long non-coding RNAs and its biological functions
Evidence accumulated over the past decade shows that long non-coding RNAs (lncRNAs)
are widely expressed and have key roles in gene regulation. Recent studies have begun to …
are widely expressed and have key roles in gene regulation. Recent studies have begun to …
Cellular functions of long noncoding RNAs
A diverse catalog of long noncoding RNAs (lncRNAs), which lack protein-coding potential,
are transcribed from the mammalian genome. They are emerging as important regulators in …
are transcribed from the mammalian genome. They are emerging as important regulators in …
Functional classification and experimental dissection of long noncoding RNAs
Over the last decade, it has been increasingly demonstrated that the genomes of many
species are pervasively transcribed, resulting in the production of numerous long noncoding …
species are pervasively transcribed, resulting in the production of numerous long noncoding …
Noncoding RNA: RNA regulatory networks in cancer
JJ Chan, Y Tay - International journal of molecular sciences, 2018 - mdpi.com
Noncoding RNAs (ncRNAs) constitute the majority of the human transcribed genome. This
largest class of RNA transcripts plays diverse roles in a multitude of cellular processes, and …
largest class of RNA transcripts plays diverse roles in a multitude of cellular processes, and …
NEAT1 is essential for metabolic changes that promote breast cancer growth and metastasis
Accelerated glycolysis is the main metabolic change observed in cancer, but the underlying
molecular mechanisms and their role in cancer progression remain poorly understood …
molecular mechanisms and their role in cancer progression remain poorly understood …
The lncRNA Neat1 promotes activation of inflammasomes in macrophages
The inflammasome has an essential function in innate immune, responding to a wide variety
of stimuli. Here we show that the lncRNA Neat1 promotes the activation of several …
of stimuli. Here we show that the lncRNA Neat1 promotes the activation of several …