Circadian rhythm regulates the function of immune cells and participates in the development of tumors

Y Zeng, Z Guo, M Wu, F Chen, L Chen - Cell death discovery, 2024 - nature.com
Circadian rhythms are present in almost all cells and play a crucial role in regulating various
biological processes. Maintaining a stable circadian rhythm is essential for overall health …

Circadian disruption and mental health: the chronotherapeutic potential of microbiome-based and dietary strategies

P Codoñer-Franch, M Gombert… - International journal of …, 2023 - mdpi.com
Mental illness is alarmingly on the rise, and circadian disruptions linked to a modern lifestyle
may largely explain this trend. Impaired circadian rhythms are associated with mental …

The impact of aging and oxidative stress in metabolic and nervous system disorders: programmed cell death and molecular signal transduction crosstalk

K Maiese - Frontiers in immunology, 2023 - frontiersin.org
Life expectancy is increasing throughout the world and coincides with a rise in non-
communicable diseases (NCDs), especially for metabolic disease that includes diabetes …

Molecular mechanisms of tumour development in glioblastoma: an emerging role for the circadian clock

N Nelson, A Relógio - NPJ Precision Oncology, 2024 - nature.com
Glioblastoma is one of the most lethal cancers with current therapeutic options lacking major
successes. This underlines the necessity to understand glioblastoma biology on other levels …

The relationship between circadian rhythm and cancer disease

C Munteanu, S Turti, L Achim, R Muresan… - International Journal of …, 2024 - mdpi.com
The circadian clock regulates biological cycles across species and is crucial for
physiological activities and biochemical reactions, including cancer onset and development …

The metabolic basis for nervous system dysfunction in alzheimer's disease, parkinson's disease, and huntington's disease

K Maiese - Current neurovascular research, 2023 - benthamdirect.com
Disorders of metabolism affect multiple systems throughout the body but may have the
greatest impact on both central and peripheral nervous systems. Currently available …

The role of circadian clock in regulating cell functions: implications for diseases

Y Lin, L He, Y Cai, X Wang, S Wang, F Li - MedComm, 2024 - Wiley Online Library
The circadian clock system orchestrates daily behavioral and physiological rhythms,
facilitating adaptation to environmental and internal oscillations. Disruptions in circadian …

Innovative therapeutic strategies for cardiovascular disease

K Maiese - EXCLI journal, 2023 - pmc.ncbi.nlm.nih.gov
As a significant non-communicable disease, cardiovascular disease is the leading cause of
death for both men and women, comprises almost twenty percent of deaths in most racial …

Circadian de (regulation) in physiology: implications for disease and treatment

LVM de Assis, A Kramer - Genes & Development, 2024 - genesdev.cshlp.org
Time plays a crucial role in the regulation of physiological processes. Without a temporal
control system, animals would be unprepared for cyclic environmental changes, negatively …

[HTML][HTML] Abnormal Histopathological Expression of Klotho, Ferroptosis, and Circadian Clock Regulators in Pancreatic Ductal Adenocarcinoma: Prognostic Implications …

C García-Montero, O Fraile-Martinez, D Cobo-Prieto… - Biomolecules, 2024 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is an extremely lethal tumor with increasing
incidence, presenting numerous clinical challenges. The histopathological examination of …