The post-GWAS era: from association to function
MD Gallagher, AS Chen-Plotkin - The American Journal of Human …, 2018 - cell.com
During the past 12 years, genome-wide association studies (GWASs) have uncovered
thousands of genetic variants that influence risk for complex human traits and diseases. Yet …
thousands of genetic variants that influence risk for complex human traits and diseases. Yet …
A review of feature selection techniques in bioinformatics
Feature selection techniques have become an apparent need in many bioinformatics
applications. In addition to the large pool of techniques that have already been developed in …
applications. In addition to the large pool of techniques that have already been developed in …
Causal relationship between gut microbiota and cancers: a two-sample Mendelian randomisation study
Y Long, L Tang, Y Zhou, S Zhao, H Zhu - BMC medicine, 2023 - Springer
Background Evidence from observational studies and clinical trials suggests that the gut
microbiota is associated with cancer. However, the causal association between gut …
microbiota is associated with cancer. However, the causal association between gut …
Second-generation PLINK: rising to the challenge of larger and richer datasets
Background PLINK 1 is a widely used open-source C/C++ toolset for genome-wide
association studies (GWAS) and research in population genetics. However, the steady …
association studies (GWAS) and research in population genetics. However, the steady …
Haploview: analysis and visualization of LD and haplotype maps
Research over the last few years has revealed significant haplotype structure in the human
genome. The characterization of these patterns, particularly in the context of medical genetic …
genome. The characterization of these patterns, particularly in the context of medical genetic …
Initial sequencing and comparative analysis of the mouse genome
European Bioinformatics Institute: Birney Ewan 3 … - Nature, 2002 - nature.com
The sequence of the mouse genome is a key informational tool for understanding the
contents of the human genome and a key experimental tool for biomedical research. Here …
contents of the human genome and a key experimental tool for biomedical research. Here …
Sharing clusters among related groups: Hierarchical Dirichlet processes
We propose the hierarchical Dirichlet process (HDP), a nonparametric Bayesian model for
clustering problems involving multiple groups of data. Each group of data is modeled with a …
clustering problems involving multiple groups of data. Each group of data is modeled with a …
Status and prospects of genome‐wide association studies in plants
Genome‐wide association studies (GWAS) have developed into a powerful and ubiquitous
tool for the investigation of complex traits. In large part, this was fueled by advances in …
tool for the investigation of complex traits. In large part, this was fueled by advances in …
Springer series in statistics
The idea for this book came from the time the authors spent at the Statistics and Applied
Mathematical Sciences Institute (SAMSI) in Research Triangle Park in North Carolina …
Mathematical Sciences Institute (SAMSI) in Research Triangle Park in North Carolina …
The international HapMap project
RA Gibbs, JW Belmont, P Hardenbol, TD Willis, FL Yu… - 2003 - deepblue.lib.umich.edu
The goal of the International HapMap Project is to determine the common patterns of DNA
sequence variation in the human genome and to make this information freely available in …
sequence variation in the human genome and to make this information freely available in …