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A guide to current methodology and usage of reverse vaccinology towards in silico vaccine discovery
SJ Goodswen, PJ Kennedy… - FEMS Microbiology …, 2023 - academic.oup.com
Reverse vaccinology (RV) was described at its inception in 2000 as an in silico process that
starts from the genomic sequence of the pathogen and ends with a list of potential protein …
starts from the genomic sequence of the pathogen and ends with a list of potential protein …
In silico design and immunoinformatics analysis of a universal multi-epitope vaccine against monkeypox virus
Monkeypox virus (MPXV) outbreaks have been reported in various countries worldwide;
however, there is no specific vaccine against MPXV. In this study, therefore, we employed …
however, there is no specific vaccine against MPXV. In this study, therefore, we employed …
Immunoinformatics design of a structural proteins driven multi-epitope candidate vaccine against different SARS-CoV-2 variants based on fynomer
J Sarvmeili, B Baghban Kohnehrouz, A Gholizadeh… - Scientific Reports, 2024 - nature.com
The ideal vaccines for combating diseases that may emerge in the future require more than
simply inactivating a few pathogenic strains. This study aims to provide a peptide-based …
simply inactivating a few pathogenic strains. This study aims to provide a peptide-based …
Designing a novel multi‑epitope vaccine against Ebola virus using reverse vaccinology approach
M Alizadeh, H Amini-Khoei, S Tahmasebian… - Scientific reports, 2022 - nature.com
Ebola virus (EBOV) is a dangerous zoonotic infectious disease. To date, more than 25 EBOV
outbreaks have been documented, the majority of which have occurred in Central Africa …
outbreaks have been documented, the majority of which have occurred in Central Africa …
Contriving multi-epitope vaccine ensemble for monkeypox disease using an immunoinformatics approach
The current global outbreak of monkeypox (MPX) disease, caused by Monkeypox virus
(MPXV), has resulted in 16 thousand infection cases, five deaths, and has been declared a …
(MPXV), has resulted in 16 thousand infection cases, five deaths, and has been declared a …
Immunoinformatics-guided approach for designing a pan-proteome multi-epitope subunit vaccine against African swine fever virus
Despite being identified over a hundred years ago, there is still no commercially available
vaccine for the highly contagious and deadly African swine fever virus (ASFV). This study …
vaccine for the highly contagious and deadly African swine fever virus (ASFV). This study …
[HTML][HTML] Isolation, characterization and pharmacological potentials of methanol extract of Cassia fistula leaves: evidenced from mice model along with molecular …
The purpose of the current investigation was to conduct a detailed analysis of the chemical
components and medicinal properties of the methanolic crude extract derived from the …
components and medicinal properties of the methanolic crude extract derived from the …
[HTML][HTML] Bioactive compounds extracted from leaves of G. cyanocarpa using various solvents in chromatographic separation showed anti-cancer and anti-microbial …
MA TAHER, AA LABONI, SA SHOMPA… - Chinese Journal of …, 2023 - Elsevier
The study was carried out to determine the possible bioactive compounds from Ethanol,
Methanol, Petroleum ether, and Dichloromethane fractions of Glycosmic cyanocarpa (G …
Methanol, Petroleum ether, and Dichloromethane fractions of Glycosmic cyanocarpa (G …
Predicting TCR sequences for unseen antigen epitopes using structural and sequence features
H Ji, XX Wang, Q Zhang, C Zhang… - Briefings in …, 2024 - academic.oup.com
T-cell receptor (TCR) recognition of antigens is fundamental to the adaptive immune
response. With the expansion of experimental techniques, a substantial database of …
response. With the expansion of experimental techniques, a substantial database of …
[HTML][HTML] Development of an ancestral DC and TLR4-inducing multi-epitope peptide vaccine against the spike protein of SARS-CoV and SARS-CoV-2 using the …
The oldest human coronavirus that started pandemics is severe acute respiratory syndrome
virus (SARS-CoV). While SARS-CoV was eradicated, its new version, SARS-CoV2, caused …
virus (SARS-CoV). While SARS-CoV was eradicated, its new version, SARS-CoV2, caused …