Supramolecular systems for bioapplications: recent research progress in China

YY Liu, XY Yu, YC Pan, H Yin, S Chao, Y Li… - Science China …, 2024 - Springer
Supramolecular systems feature dynamic, reversible and stimuli-responsive characteristics,
which are not easily achieved by molecular entities. The last decade has witnessed …

Overcoming barriers with non-covalent interactions: supramolecular recognition of adamantyl cucurbit [n] uril assemblies for medical applications

M Alešković, M Šekutor - RSC Medicinal Chemistry, 2024 - pubs.rsc.org
Adamantane, a staple in medicinal chemistry, recently became a cornerstone of a
supramolecular host–guest drug delivery system, ADA/CB [n]. Owing to a good fit between …

Macrocycle-based antibacterial materials

X Wang, L Ma, C Li, YW Yang - Chemistry of Materials, 2024 - ACS Publications
Bacterial infection, the cause of many diseases, has become one of the most severe global
public health threats. The emergence of antimicrobial resistance poses a significant …

Alleviating recombinant tissue plasminogen activator‐induced hemorrhagic transformation in ischemic stroke via targeted delivery of a ferroptosis inhibitor

YQ Geng, LN Qiu, YQ Cheng, JJ Li, YL Ma… - Advanced …, 2024 - Wiley Online Library
Intravenous thrombolysis with recombinant tissue plasminogen activator (rtPA) is the primary
treatment for ischemic stroke. However, rtPA treatment can substantially increase blood …

Pillarurilarenes: Glycoluril-Expanded Pillararenes

C Ruan, Z Li, W Lin, R Wang, W ** biotechnology. Cell-free gene expression (CFE) systems offer a …

Cucurbit [7] uril-based host–guest complexes for improving bioavailability and reducing side effects of piroxicam

Y Wang, X Yang, J Luo, S Yi, T Guo, Y Liao… - International Journal of …, 2024 - Elsevier
Piroxicam (PX) is a nonsteroidal anti-inflammatory drug (NSAID) commonly associated with
gastrointestinal (GI) injuries, including dyspepsia, heartburn, inflammation, bleeding …

Recent progress in site-selective modification of peptides and proteins using macrocycles

YC Wang, SC Bai, WL Ye, J Jiang, G Li - Bioconjugate Chemistry, 2024 - ACS Publications
Peptides and proteins undergo crucial modifications to alter their physicochemical
properties to expand their applications in diverse fields. Various techniques, such as …

Extended Sulfo-Pillar [6] arenes─ a New Host Family and Its Application in the Binding of Direct Oral Anticoagulants

CR Wilson, AO Puckett, IM Murray… - Journal of the …, 2024 - ACS Publications
Herein, we report the synthesis of extended sulfo-pillar [6] arenes (sP6), a new host class
with a pedigree in salt tolerance and ultrahigh binding affinity toward multiple drug classes …

Cucurbit [7] uril-Catalyzed Beckmann Rearrangement of Arylketoximes

D Liu, Y Fan, M Liu, Q Ge, R Gao, H Cong - Organic Letters, 2024 - ACS Publications
With the existence of cucurbit [7] uril (Q [7]), a supramolecular catalysis strategy for the
Beckmann rearrangement of aryl ketoximes to N-substituted amides was successfully …