The sleep-immune crosstalk in health and disease
Sleep-immune interactions are well-known phenomena in everyday life and folk wisdom.
There is no doubt that an infection makes us tired and increases the desire to sleep, and a …
There is no doubt that an infection makes us tired and increases the desire to sleep, and a …
Role of sleep deprivation in immune-related disease risk and outcomes
Modern societies are experiencing an increasing trend of reduced sleep duration, with
nocturnal slee** time below the recommended ranges for health. Epidemiological and …
nocturnal slee** time below the recommended ranges for health. Epidemiological and …
Sleep and inflammation: partners in sickness and in health
MR Irwin - Nature Reviews Immunology, 2019 - nature.com
The discovery of reciprocal connections between the central nervous system, sleep and the
immune system has shown that sleep enhances immune defences and that afferent signals …
immune system has shown that sleep enhances immune defences and that afferent signals …
Sleep health: reciprocal regulation of sleep and innate immunity
Sleep disturbances including insomnia independently contribute to risk of inflammatory
disorders and major depressive disorder. This review and overview provides an integrated …
disorders and major depressive disorder. This review and overview provides an integrated …
Evidence for an immune response in major depression: a review and hypothesis
M Maes - Progress in Neuro-Psychopharmacology and …, 1995 - Elsevier
1. This paper reviews recent findings on cellular and humoral immunity and inflammatory
markers in depression. 2. 2. It is shown that major depression may be accompanied by …
markers in depression. 2. 2. It is shown that major depression may be accompanied by …
How (and why) the immune system makes us sleep
Good sleep is necessary for physical and mental health. For example, sleep loss impairs
immune function, and sleep is altered during infection. Immune signalling molecules are …
immune function, and sleep is altered during infection. Immune signalling molecules are …
The bidirectional relationship between sleep and immunity against infections
EG Ibarra-Coronado… - Journal of …, 2015 - Wiley Online Library
Sleep is considered an important modulator of the immune response. Thus, a lack of sleep
can weaken immunity, increasing organism susceptibility to infection. For instance, shorter …
can weaken immunity, increasing organism susceptibility to infection. For instance, shorter …
Exposure to acute stress induces brain interleukin-1β protein in the rat
Peripheral immune stimulation such as that provided by lipopolysaccharide (LPS) has been
reported to increase brain levels of IL-1β mRNA, immunoreactivity, and bioactivity. Stressors …
reported to increase brain levels of IL-1β mRNA, immunoreactivity, and bioactivity. Stressors …
Relationships between interleukin-6 activity, acute phase proteins, and function of the hypothalamic-pituitary-adrenal axis in severe depression
Recent studies from this laboratory have provided some evidence that major depression, in
particular melancholia, may be accompanied by an immune response. The present study …
particular melancholia, may be accompanied by an immune response. The present study …
Effects of sleep and sleep loss on immunity and cytokines
M Irwin - Brain, behavior, and immunity, 2002 - Elsevier
Sleep is hypothesized to be a restorative process that is important for the proper functioning
of the immune system. Severity of disordered sleep in depressed-and alcoholic subjects …
of the immune system. Severity of disordered sleep in depressed-and alcoholic subjects …