Objectives: Chordoma is a rare bone malignancy that affects the spine and skull base.
Treatment dilemma leads to a high rate of local relapse and distant metastases. Molecular …

Chordoma is a rare tumor that occurs along the axial spine in pediatrics and adults, with an
incidence of approximately 350 cases per year in the United States. While typically …

Primary bone cancers are extremely rare neoplasms, accounting for fewer than 0.2% of all
cancers. The evaluation and treatment of patients with bone cancers requires a …

Background Sacral chordomas are rare low-to-intermediate grade malignant tumours, which
arise from remnants of the embryonic notochord. This review explores prognostic factors in …

Little data exists comparing endoscopic endonasal approaches to pathology of the anterior
skull base with more traditional transcranial and transsphenoidal microscopic approaches …

Chordoma is a rare malignant tumor with predilection for the sacrum. A favorable outcome
depends on early diagnosis and surgical excision with tumor free margins. Aim To review …

BACKGROUND: The current management paradigm for clival chordomas includes
cytoreductive surgery with adjuvant radiotherapy. Surgical approaches have traditionally …

Objective chordomas are rare bone tumors with few therapeutic options. Skull base and
sacrum are the two most common origin sites. Immunotherapies are emerging as the most …

BACKGROUND Local recurrence rates are high in sacral chordoma patients. Adjuvant
radiotherapy may play a role in increasing local control. Patients with locally recurrent …

Background Chordoma in the spine is relatively rare, and minimal information has been
published in the literature regarding this subject. Moreover, there are controversies over …