Gut microbiome, big data and machine learning to promote precision medicine for cancer
The gut microbiome has been implicated in cancer in several ways, as specific microbial
signatures are known to promote cancer development and influence safety, tolerability and …
signatures are known to promote cancer development and influence safety, tolerability and …
Precision medicine in the era of artificial intelligence: implications in chronic disease management
Aberrant metabolism is the root cause of several serious health issues, creating a huge
burden to health and leading to diminished life expectancy. A dysregulated metabolism …
burden to health and leading to diminished life expectancy. A dysregulated metabolism …
A longitudinal big data approach for precision health
SM Schüssler-Fiorenza Rose, K Contrepois… - Nature medicine, 2019 - nature.com
Precision health relies on the ability to assess disease risk at an individual level, detect early
preclinical conditions and initiate preventive strategies. Recent technological advances in …
preclinical conditions and initiate preventive strategies. Recent technological advances in …
[HTML][HTML] Profound perturbation of the metabolome in obesity is associated with health risk
Obesity is a heterogeneous phenotype that is crudely measured by body mass index (BMI).
There is a need for a more precise yet portable method of phenoty** and categorizing risk …
There is a need for a more precise yet portable method of phenoty** and categorizing risk …
Practicing precision medicine with intelligently integrative clinical and multi-omics data analysis
Z Ahmed - Human genomics, 2020 - Springer
Precision medicine aims to empower clinicians to predict the most appropriate course of
action for patients with complex diseases like cancer, diabetes, cardiomyopathy, and COVID …
action for patients with complex diseases like cancer, diabetes, cardiomyopathy, and COVID …
Cooperative learning for multiview analysis
We propose a method for supervised learning with multiple sets of features (“views”). The
multiview problem is especially important in biology and medicine, where “-omics” data …
multiview problem is especially important in biology and medicine, where “-omics” data …
The future of precision medicine in the cure of Alzheimer's disease
This decade has seen the beginning of ground-breaking conceptual shifts in the research of
Alzheimer's disease (AD), which acknowledges risk elements and the evolving wide …
Alzheimer's disease (AD), which acknowledges risk elements and the evolving wide …
Precision medicine integrating whole-genome sequencing, comprehensive metabolomics, and advanced imaging
Genome sequencing has established clinical utility for rare disease diagnosis. While
increasing numbers of individuals have undergone elective genome sequencing, a …
increasing numbers of individuals have undergone elective genome sequencing, a …
Metabolomics in the clinic: A review of the shared and unique features of untargeted metabolomics for clinical research and clinical testing
AD Kennedy, BM Wittmann, AM Evans… - Journal of Mass …, 2018 - Wiley Online Library
Metabolomics is the untargeted measurement of the metabolome, which is composed of the
complement of small molecules detected in a biological sample. As such, metabolomic …
complement of small molecules detected in a biological sample. As such, metabolomic …
Precision medicine and the problem of structural injustice
Many countries currently invest in technologies and data infrastructures to foster precision
medicine (PM), which is hoped to better tailor disease treatment and prevention to individual …
medicine (PM), which is hoped to better tailor disease treatment and prevention to individual …