Among age-related diseases, cardiovascular and cerebrovascular diseases are major
causes of death. Vascular dysfunction is a key characteristic of these diseases wherein age …

Sarcopenia, the age-related loss of muscle mass and function, imposes a dramatic burden
on individuals and society. The development of preventive and therapeutic strategies …

We tested the hypothesis that carotid artery stiffening with ageing is associated with
transforming growth factor‐β1 (TGF‐β1)‐related increases in adventitial collagen and …

Aging is associated with a progressive decline in the capacity for physical activity. Central to
this decline is a reduction in the maximal rate of oxygen utilization, or V O2 max. This critical …

Blood flow capacity in skeletal muscle declines with age. Reduced blood flow capacity may
be related to decline in the maximal vasodilatory capacity of the resistance vasculature. This …

Ageing reduces endothelium‐dependent vasodilatation in humans and animals, and in
humans, exercise training reverses the ageing‐associated reduction in endothelium …

We determined whether aging diminishes bone blood flow and impairs endothelium‐
dependent vasodilation. Femoral perfusion was lower in old animals, as well as …

To determine the effect of age on quadriceps muscle blood flow (QMBF), leg vascular
resistance (LVR), and maximum oxygen uptake (QV̇O2 max), a thermal dilution technique …

Age-related reductions in basal limb blood flow and vascular conductance are associated
with the metabolic syndrome, functional impairments, and osteoporosis. We tested the …

Aging is associated with inspiratory muscle dysfunction; however, the impact of aging on
diaphragm blood flow (BF) regulation, and whether sex differences exist, is unknown. We …