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Deep learning-enabled virtual histological staining of biological samples
Histological staining is the gold standard for tissue examination in clinical pathology and life-
science research, which visualizes the tissue and cellular structures using chromatic dyes or …
science research, which visualizes the tissue and cellular structures using chromatic dyes or …
Artificial intelligence to identify genetic alterations in conventional histopathology
Precision oncology relies on the identification of targetable molecular alterations in tumor
tissues. In many tumor types, a limited set of molecular tests is currently part of standard …
tissues. In many tumor types, a limited set of molecular tests is currently part of standard …
Deep learning-based virtual staining, segmentation, and classification in label-free photoacoustic histology of human specimens
In pathological diagnostics, histological images highlight the oncological features of excised
specimens, but they require laborious and costly staining procedures. Despite recent …
specimens, but they require laborious and costly staining procedures. Despite recent …
Noninvasive virtual biopsy using micro-registered optical coherence tomography (OCT) in human subjects
Histological hematoxylin and eosin–stained (H&E) tissue sections are used as the gold
standard for pathologic detection of cancer, tumor margin detection, and disease diagnosis …
standard for pathologic detection of cancer, tumor margin detection, and disease diagnosis …
Virtual staining for histology by deep learning
In pathology and biomedical research, histology is the cornerstone method for tissue
analysis. Currently, the histological workflow consumes plenty of chemicals, water, and time …
analysis. Currently, the histological workflow consumes plenty of chemicals, water, and time …
An ultraviolet‐transparent ultrasound transducer enables high‐resolution label‐free photoacoustic histopathology
Ultraviolet photoacoustic microscopy (UV‐PAM), based on the high intrinsic optical
absorption of DNA/RNA, holds great promise for intraoperative label‐free histopathological …
absorption of DNA/RNA, holds great promise for intraoperative label‐free histopathological …
Virtual histological staining of unlabeled autopsy tissue
Traditional histochemical staining of post-mortem samples often confronts inferior staining
quality due to autolysis caused by delayed fixation of cadaver tissue, and such chemical …
quality due to autolysis caused by delayed fixation of cadaver tissue, and such chemical …
Recent advances in deep-learning-enhanced photoacoustic imaging
Photoacoustic imaging (PAI), recognized as a promising biomedical imaging modality for
preclinical and clinical studies, uniquely combines the advantages of optical and ultrasound …
preclinical and clinical studies, uniquely combines the advantages of optical and ultrasound …
Deep learning-enabled realistic virtual histology with ultraviolet photoacoustic remote sensing microscopy
The goal of oncologic surgeries is complete tumor resection, yet positive margins are
frequently found postoperatively using gold standard H&E-stained histology methods …
frequently found postoperatively using gold standard H&E-stained histology methods …
Virtual histological staining of label-free total absorption photoacoustic remote sensing (TA-PARS)
Histopathological visualizations are a pillar of modern medicine and biological research.
Surgical oncology relies exclusively on post-operative histology to determine definitive …
Surgical oncology relies exclusively on post-operative histology to determine definitive …