Proteins are dynamic entities, and they possess an inherent flexibility that allows them to
function through molecular interactions within the cell, among cells and even between …

Group A streptococcus (Streptococcus pyogenes) is an exclusively human pathogen that
causes a wide spectrum of diseases ranging from pharyngitis, to impetigo, to toxic shock, to …

Streptococcal pyrogenic exotoxin B (SpeB) is a protease secreted by group A streptococci
and known to degrade a wide range of host and GAS proteins in vitro. Although the role of …

Streptococcal pyrogenic exotoxin B (SpeB) is a cysteine protease expressed during group A
streptococcal infection that represents a major virulence factor. Although subject to several …

Streptococcal pyogenic exotoxins (Spe proteins) secreted by Streptococcus pyogenes
(group A Streptococcus, GAS) are responsible for scarlet fever and streptococcal toxic shock …

Streptococcus pyogenes, or group A Streptococcus (GAS), a gram-positive bacterium, is
implicated in a wide range of clinical manifestations and life-threatening diseases. One of …

Periodontitis is a chronic inflammatory disease that affects an estimated 20–50% of the
world's population and can lead to high follow-up costs for the healthcare system. The …

Streptococcal cysteine protease (SpeB), the major secreted protease produced by group A
streptococcus (GAS), cleaves both host and bacterial proteins and contributes importantly to …

Halolysin SptA from haloarchaeon Natrinema sp. J7 consists of a subtilisin-like catalytic
domain and a C-terminal extension (CTE) containing two cysteine residues. In this report …

Cruzain is a member of the papain/cathepsin L family of cysteine proteases, and the major
cysteine protease of the protozoan Trypanosoma cruzi, the causative agent of Chagas …