Advances and challenges in synthetic biology for mosquito control

SC Weng, RA Masri, OS Akbari - Trends in parasitology, 2024 - cell.com
Mosquito-borne illnesses represent a significant global health peril, resulting in
approximately one million fatalities annually. West Nile, dengue, Zika, and malaria are …

Y and W chromosome assemblies: approaches and discoveries

M Tomaszkiewicz, P Medvedev, KD Makova - Trends in genetics, 2017 - cell.com
Hundreds of vertebrate genomes have been sequenced and assembled to date. However,
most sequencing projects have ignored the sex chromosomes unique to the heterogametic …

AY chromosome-linked genome editor for efficient population suppression in the malaria vector Anopheles gambiae

I Tolosana, K Willis, M Gribble, L Phillimore… - Nature …, 2025 - nature.com
Genetic control–the deliberate introduction of genetic traits to control a pest or vector
population–offers a powerful tool to augment conventional mosquito control tools that have …

Assembly of the threespine stickleback Y chromosome reveals convergent signatures of sex chromosome evolution

CL Peichel, SR McCann, JA Ross, AFS Naftaly… - Genome biology, 2020 - Springer
Background Heteromorphic sex chromosomes have evolved repeatedly across diverse
species. Suppression of recombination between X and Y chromosomes leads to …

Nix alone is sufficient to convert female Aedes aegypti into fertile males and myo-sex is needed for male flight

A Aryan, MAE Anderson, JK Biedler, Y Qi… - Proceedings of the …, 2020 - pnas.org
A dominant male-determining locus (M-locus) establishes the male sex (M/m) in the yellow
fever mosquito, Aedes aegypti. Nix, a gene in the M-locus, was shown to be a male …

Heterochromatin Is Not the Only Place for satDNAs: The High Diversity of satDNAs in the Euchromatin of the Beetle Chrysolina americana (Coleoptera …

JM Rico-Porras, P Mora, T Palomeque, EE Montiel… - Genes, 2024 - mdpi.com
The satellitome of the beetle Chrysolina americana Linneo, 1758 has been characterized
through chromosomal analysis, genomic sequencing, and bioinformatics tools. C-banding …

De novo assembly of a young Drosophila Y chromosome using single-molecule sequencing and chromatin conformation capture

S Mahajan, KHC Wei, MJ Nalley, L Gibilisco… - PLoS …, 2018 - journals.plos.org
While short-read sequencing technology has resulted in a sharp increase in the number of
species with genome assemblies, these assemblies are typically highly fragmented …

A maleness gene in the malaria mosquito Anopheles gambiae

E Krzywinska, NJ Dennison, GJ Lycett, J Krzywinski - Science, 2016 - science.org
The molecular pathways controlling gender are highly variable and have been identified in
only a few nonmammalian model species. In many insects, maleness is conferred by a Y …

Gene drive: evolved and synthetic

A Burt, A Crisanti - ACS chemical biology, 2018 - ACS Publications
Drive is a process of accelerated inheritance from one generation to the next that allows
some genes to spread rapidly through populations even if they do not contribute to or …

Coalescent Analysis of Phylogenomic Data Confidently Resolves the Species Relationships in the Anopheles gambiae Species Complex

Y Thawornwattana, D Dalquen… - Molecular biology and …, 2018 - academic.oup.com
Deep coalescence and introgression make it challenging to infer phylogenetic relationships
among closely related species that arose through radiative speciation events. Despite …