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Advances and challenges in synthetic biology for mosquito control
SC Weng, RA Masri, OS Akbari - Trends in parasitology, 2024 - cell.com
Mosquito-borne illnesses represent a significant global health peril, resulting in
approximately one million fatalities annually. West Nile, dengue, Zika, and malaria are …
approximately one million fatalities annually. West Nile, dengue, Zika, and malaria are …
Y and W chromosome assemblies: approaches and discoveries
Hundreds of vertebrate genomes have been sequenced and assembled to date. However,
most sequencing projects have ignored the sex chromosomes unique to the heterogametic …
most sequencing projects have ignored the sex chromosomes unique to the heterogametic …
AY chromosome-linked genome editor for efficient population suppression in the malaria vector Anopheles gambiae
I Tolosana, K Willis, M Gribble, L Phillimore… - Nature …, 2025 - nature.com
Genetic control–the deliberate introduction of genetic traits to control a pest or vector
population–offers a powerful tool to augment conventional mosquito control tools that have …
population–offers a powerful tool to augment conventional mosquito control tools that have …
Assembly of the threespine stickleback Y chromosome reveals convergent signatures of sex chromosome evolution
Background Heteromorphic sex chromosomes have evolved repeatedly across diverse
species. Suppression of recombination between X and Y chromosomes leads to …
species. Suppression of recombination between X and Y chromosomes leads to …
Nix alone is sufficient to convert female Aedes aegypti into fertile males and myo-sex is needed for male flight
A Aryan, MAE Anderson, JK Biedler, Y Qi… - Proceedings of the …, 2020 - pnas.org
A dominant male-determining locus (M-locus) establishes the male sex (M/m) in the yellow
fever mosquito, Aedes aegypti. Nix, a gene in the M-locus, was shown to be a male …
fever mosquito, Aedes aegypti. Nix, a gene in the M-locus, was shown to be a male …
Heterochromatin Is Not the Only Place for satDNAs: The High Diversity of satDNAs in the Euchromatin of the Beetle Chrysolina americana (Coleoptera …
The satellitome of the beetle Chrysolina americana Linneo, 1758 has been characterized
through chromosomal analysis, genomic sequencing, and bioinformatics tools. C-banding …
through chromosomal analysis, genomic sequencing, and bioinformatics tools. C-banding …
De novo assembly of a young Drosophila Y chromosome using single-molecule sequencing and chromatin conformation capture
While short-read sequencing technology has resulted in a sharp increase in the number of
species with genome assemblies, these assemblies are typically highly fragmented …
species with genome assemblies, these assemblies are typically highly fragmented …
A maleness gene in the malaria mosquito Anopheles gambiae
E Krzywinska, NJ Dennison, GJ Lycett, J Krzywinski - Science, 2016 - science.org
The molecular pathways controlling gender are highly variable and have been identified in
only a few nonmammalian model species. In many insects, maleness is conferred by a Y …
only a few nonmammalian model species. In many insects, maleness is conferred by a Y …
Gene drive: evolved and synthetic
Drive is a process of accelerated inheritance from one generation to the next that allows
some genes to spread rapidly through populations even if they do not contribute to or …
some genes to spread rapidly through populations even if they do not contribute to or …
Coalescent Analysis of Phylogenomic Data Confidently Resolves the Species Relationships in the Anopheles gambiae Species Complex
Deep coalescence and introgression make it challenging to infer phylogenetic relationships
among closely related species that arose through radiative speciation events. Despite …
among closely related species that arose through radiative speciation events. Despite …