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Respiratory epithelial cell responses to SARS-CoV-2 in COVID-19
JP Bridges, EK Vladar, H Huang, RJ Mason - Thorax, 2022 - thorax.bmj.com
COVID-19 has different clinical stages, and effective therapy depends on the location and
extent of the infection. The purpose of this review is to provide a background for …
extent of the infection. The purpose of this review is to provide a background for …
SP-A and SP-D: dual functioning immune molecules with antiviral and immunomodulatory properties
Surfactant proteins A (SP-A) and D (SP-D) are soluble innate immune molecules which
maintain lung homeostasis through their dual roles as anti-infectious and …
maintain lung homeostasis through their dual roles as anti-infectious and …
Alveolar type II cells and pulmonary surfactant in COVID-19 era
A Calkovska, M Kolomaznik… - Physiological …, 2021 - pmc.ncbi.nlm.nih.gov
In this review, we discuss the role of pulmonary surfactant in the host defense against
respiratory pathogens, including novel coronavirus SARS-CoV-2. In the lower respiratory …
respiratory pathogens, including novel coronavirus SARS-CoV-2. In the lower respiratory …
The role of pulmonary surfactants in the treatment of acute respiratory distress syndrome in COVID-19
S Wang, Z Li, X Wang, S Zhang, P Gao… - Frontiers in …, 2021 - frontiersin.org
Lung alveolar type-II (AT-II) cells produce pulmonary surfactant (PS), consisting of proteins
and lipids. The lipids in PS are primarily responsible for reducing the air-fluid surface tension …
and lipids. The lipids in PS are primarily responsible for reducing the air-fluid surface tension …
Role of respiratory epithelial cells in allergic diseases
CA Jakwerth, J Ordovas-Montanes, S Blank… - Cells, 2022 - mdpi.com
The airway epithelium provides the first line of defense to the surrounding environment.
However, dysfunctions of this physical barrier are frequently observed in allergic diseases …
However, dysfunctions of this physical barrier are frequently observed in allergic diseases …
Experimental techniques to study protein–surfactant interactions: New insights into competitive adsorptions via drop subphase and interface exchange
Protein surfactant (Psingle bond S) interactions is an essential topic for many fundamental
and technological applications such as life science, nanobiotechnology processes, food …
and technological applications such as life science, nanobiotechnology processes, food …
Host cell entry mediators implicated in the cellular tropism of SARS-CoV-2, the pathophysiology of COVID-19 and the identification of microRNAs that can modulate …
The pathophysiology of coronavirus disease 2019 (COVID-19) is mainly dependent on the
underlying mechanisms that mediate the entry of severe acute respiratory syndrome …
underlying mechanisms that mediate the entry of severe acute respiratory syndrome …
Human surfactant protein A inhibits SARS-CoV-2 infectivity and alleviates lung injury in a mouse infection model
IB Jacob, A Gemmiti, W **ong, E Reynolds… - Frontiers in …, 2024 - frontiersin.org
Introduction SARS coronavirus 2 (SARS-CoV-2) infects human angiotensin-converting
enzyme 2 (hACE2)-expressing lung epithelial cells through its spike (S) protein. The S …
enzyme 2 (hACE2)-expressing lung epithelial cells through its spike (S) protein. The S …
Pulmonary surfactant as a versatile biomaterial to fight COVID-19
The COVID-19 pandemic has wielded an enormous pressure on global health care systems,
economics and politics. Ongoing vaccination campaigns effectively attenuate viral …
economics and politics. Ongoing vaccination campaigns effectively attenuate viral …
Lung surfactant proteins as potential targets of prallethrin: an in silico approach
Object Prallethrin is a pyrethroid-based insecticide, commonly used as a liquid vaporizer in
household, schools, and offices to repel mosquitoes. Due to worldwide application, human …
household, schools, and offices to repel mosquitoes. Due to worldwide application, human …