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Novel antimicrobial agents for combating antibiotic-resistant bacteria
Antibiotic therapy has become increasingly ineffective against bacterial infections due to the
rise of resistance. In particular, ESKAPE pathogens (Enterococcus faecium, Staphylococcus …
rise of resistance. In particular, ESKAPE pathogens (Enterococcus faecium, Staphylococcus …
Phage therapy in the postantibiotic era
Antibiotic resistance is arguably the biggest current threat to global health. An increasing
number of infections are becoming harder or almost impossible to treat, carrying high …
number of infections are becoming harder or almost impossible to treat, carrying high …
Therapeutic potential of bacteriophage endolysins for infections caused by Gram-positive bacteria
H Liu, Z Hu, M Li, Y Yang, S Lu, X Rao - Journal of biomedical science, 2023 - Springer
Abstract Gram-positive (G+) bacterial infection is a great burden to both healthcare and
community medical resources. As a result of the increasing prevalence of multidrug-resistant …
community medical resources. As a result of the increasing prevalence of multidrug-resistant …
Resistance development to bacteriophages occurring during bacteriophage therapy
F Oechslin - Viruses, 2018 - mdpi.com
Bacteriophage (phage) therapy, ie, the use of viruses that infect bacteria as antimicrobial
agents, is a promising alternative to conventional antibiotics. Indeed, resistance to antibiotics …
agents, is a promising alternative to conventional antibiotics. Indeed, resistance to antibiotics …
Antimicrobial peptides: new hope in the war against multidrug resistance
The discovery of antibiotics marked a golden age in the revolution of human medicine.
However, decades later, bacterial infections remain a global healthcare threat, and a return …
However, decades later, bacterial infections remain a global healthcare threat, and a return …
[HTML][HTML] Phage-encoded endolysins
Due to the global emergence of antibiotic resistance, there has been an increase in
research surrounding endolysins as an alternative therapeutic. Endolysins are phage …
research surrounding endolysins as an alternative therapeutic. Endolysins are phage …
Antimicrobial peptides
The rapid increase in drug-resistant infections has presented a serious challenge to
antimicrobial therapies. The failure of the most potent antibiotics to kill “superbugs” …
antimicrobial therapies. The failure of the most potent antibiotics to kill “superbugs” …
Antibiotic alternatives: the substitution of antibiotics in animal husbandry?
G Cheng, H Hao, S **e, X Wang, M Dai… - Frontiers in …, 2014 - frontiersin.org
It is a common practice for decades to use of sub-therapeutic dose of antibiotics in food-
animal feeds to prevent animals from diseases and to improve production performance in …
animal feeds to prevent animals from diseases and to improve production performance in …
[HTML][HTML] Treating bacterial infections with bacteriophage-based enzybiotics: in vitro, in vivo and clinical application
Over the past few decades, we have witnessed a surge around the world in the emergence
of antibiotic-resistant bacteria. This global health threat arose mainly due to the overuse and …
of antibiotic-resistant bacteria. This global health threat arose mainly due to the overuse and …
The antimicrobial peptide ZY4 combats multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii infection
J Mwangi, Y Yin, G Wang, M Yang, Y Li… - Proceedings of the …, 2019 - pnas.org
The emergence of carbapenem-resistant Acinetobacter baumannii and Pseudomonas
aeruginosa raises fears of untreatable infections and poses the greatest health threats …
aeruginosa raises fears of untreatable infections and poses the greatest health threats …