CD69 is a membrane‐bound, type II C‐lectin receptor. It is a classical early marker of
lymphocyte activation due to its rapid appearance on the surface of the plasma membrane …

▪ Abstract Macrophages express a broad range of plasma membrane receptors that mediate
their interactions with natural and altered-self components of the host as well as a range of …

Human T cells are central effectors of immunity and cancer immunotherapy. CRISPR-based
functional studies in T cells could prioritize novel targets for drug development and improve …

Kupffer cell and macrophage (MØ) activation contributes to steatosis, inflammation, and
fibrosis in alcoholic liver disease (ALD). We found increased frequency of MØ, T cells, and …

One of the earliest cell surface antigens expressed by T cells following activation is CD69,
which is detectable within one h of ligation of the T cell receptor/CD3 complex. Once …

▪ Abstract Natural killer cells are likely to play an important role in the host defenses because
they kill virally infected or tumor cells but spare normal self-cells. The molecular mechanism …

The Ob gene product, leptin, is an adipocyte-secreted hormone that centrally regulates
weight control. However, leptin receptor is expressed not only in the central nervous system …

Leptin is an adipocyte-secreted hormone that centrally regulates weight control. However,
leptin receptor is expressed not only in the central nervous system, but also in other systems …

CD69 is an early leukocyte activation molecule expressed at sites of chronic inflammation.
The precise role of CD69 in immunity has not been elucidated owing to the absence of a …

The expression of activation antigens, namely CD25, CD69, CD71, and HLA‐DR on T cells
from 15 healthy individuals stimulated with different mitogens and specific antigens was …