Diffuse optical characterization of collagen absorption from 500 to 1700 nm

SKV Sekar, I Bargigia, AD Mora… - … of biomedical optics, 2017‏ - spiedigitallibrary.org
Reduction in scattering, high absorption, and spectral features of tissue constituents above
1000 nm could help in gaining higher spatial resolution, penetration depth, and specificity …

Broadband time domain diffuse optical reflectance spectroscopy: a review of systems, methods, and applications

S Konugolu Venkata Sekar, P Lanka, A Farina… - Applied Sciences, 2019‏ - mdpi.com
This review presents recent developments and a wide overview of broadband time domain
diffuse optical spectroscopy (TD-DOS). Various topics including physics of photon migration …

Solid phantom recipe for diffuse optics in biophotonics applications: a step towards anatomically correct 3D tissue phantoms

SKV Sekar, A Pacheco, P Martella, H Li… - Biomedical optics …, 2019‏ - opg.optica.org
We present a tissue mimicking optical phantom recipe to create robust well tested solid
phantoms. The recipe consists of black silicone pigment (absorber), silica microspheres …

MAESTROS: a multiwavelength time-domain NIRS system to monitor changes in oxygenation and oxidation state of cytochrome-C-oxidase

F Lange, L Dunne, L Hale… - IEEE Journal of Selected …, 2018‏ - ieeexplore.ieee.org
We present a multiwavelength, multichannel, time-domain near-infrared spectroscopy
system named MAESTROS. This instrument can measure absorption and scattering …

Diffuse optical characterization of the healthy human thyroid tissue and two pathological case studies

C Lindner, M Mora, P Farzam, M Squarcia… - PloS one, 2016‏ - journals.plos.org
The in vivo optical and hemodynamic properties of the healthy (n= 22) and pathological (n=
2) human thyroid tissue were measured non-invasively using a custom time-resolved …

Frequency offset Raman spectroscopy (FORS) for depth probing of diffusive media

SKV Sekar, S Mosca, A Farina, F Martelli, P Taroni… - Optics …, 2017‏ - opg.optica.org
We present a new technique, frequency offset Raman spectroscopy (FORS), to probe
Raman spectra of diffusive media in depth. The proposed methodology obtains depth …

In Vivo, Non-Invasive Characterization of Human Bone by Hybrid Broadband (600-1200 nm) Diffuse Optical and Correlation Spectroscopies

S Konugolu Venkata Sekar, M Pagliazzi, E Negredo… - PloS one, 2016‏ - journals.plos.org
Non-invasive in vivo diffuse optical characterization of human bone opens a new possibility
of diagnosing bone related pathologies. We present an in vivo characterization performed …

Broadband (550–1350 nm) diffuse optical characterization of thyroid chromophores

S Konugolu Venkata Sekar, A Farina, A Dalla Mora… - Scientific reports, 2018‏ - nature.com
Thyroid plays an important role in the endocrine system of the human body. Its
characterization by diffuse optics can open new path ways in the non-invasive diagnosis of …

Broadband diffuse optical characterization of elastin for biomedical applications

SKV Sekar, JS Beh, A Farina, A Dalla Mora, A Pifferi… - Biophysical …, 2017‏ - Elsevier
Elastin is a key structural protein of dynamic connective tissues widely found in the
extracellular matrix of skin, arteries, lungs and ligaments. It is responsible for a range of …

Evaluation of haemoglobin and cytochrome responses during forearm ischaemia using multi-wavelength time domain NIRS

F Lange, L Dunne, I Tachtsidis - Oxygen Transport to Tissue XXXIX, 2017‏ - Springer
We demonstrate the ability of a 16-wavelength time domain near-infrared spectroscopy
system to monitor changes in oxy-and deoxy haemoglobin ([HbO 2][HHb]) and the oxidation …