The hypothalamic-pituitary-adrenal (HPA) axis plays important roles in maintaining alertness
and modulating sleep. Dysfunction of this axis at any level (CRH receptor, glucocorticoid …

This review demonstrates that stress is closely related to impaired sleep in cross-sectional
studies. In particular, the anticipation of high demands or effort the next day seems …

Cortisol and inflammatory proteins are released into the blood in response to stressors and
chronic elevations of blood cortisol and inflammatory proteins may contribute to ongoing …

In response to various ethologically relevant stressors, oxytocin is released not only from
neurohypophysial terminals into the blood, but also within distinct brain regions, for example …

Acute stress is a fundamental adaptive response which enables an organism to cope with
daily threatening environmental stimuli. If prolonged and uncontrollable, the stress response …

Sleep is an important component of mammalian homeostasis, vital for the survival of self and
species. People spend at least one third of their lives asleep, yet have little understanding of …

In addition to their robust difference in trait anxiety, as illustrated by a variety of behavioral
tests, HAB and LAB rats differ in their stress co** strategies, the former being more …

The present study examined whether Lactobacillus casei strain Shirota (LcS) improves
sleep quality under psychological stress. A double-blind, placebo-controlled trial was …

Enhanced activity of the hypothalamic-pituitary-adrenal (HPA) axis, involving elevated
secretion of corticotropin-releasing hormone (CRH), is considered a key neurobiological …

Symptoms commonly associated with sleep loss and chronic inflammation include
sleepiness, fatigue, poor cognition, enhanced sensitivity to pain and kindling stimuli, excess …