Beyond mass spectrometry, the next step in proteomics
Proteins can be the root cause of a disease, and they can be used to cure it. The need to
identify these critical actors was recognized early (1951) by Sanger; the first biopolymer …
identify these critical actors was recognized early (1951) by Sanger; the first biopolymer …
A high-stringency blueprint of the human proteome
Abstract The Human Proteome Organization (HUPO) launched the Human Proteome Project
(HPP) in 2010, creating an international framework for global collaboration, data sharing …
(HPP) in 2010, creating an international framework for global collaboration, data sharing …
The ProteomeXchange consortium in 2020: enabling 'big data'approaches in proteomics
EW Deutsch, N Bandeira, V Sharma… - Nucleic acids …, 2020 - academic.oup.com
The ProteomeXchange (PX) consortium of proteomics resources (http://www.
proteomexchange. org) has standardized data submission and dissemination of mass …
proteomexchange. org) has standardized data submission and dissemination of mass …
A deep proteome and transcriptome abundance atlas of 29 healthy human tissues
Abstract Genome‐, transcriptome‐and proteome‐wide measurements provide insights into
how biological systems are regulated. However, fundamental aspects relating to which …
how biological systems are regulated. However, fundamental aspects relating to which …
A genome-wide transcriptomic analysis of protein-coding genes in human blood cells
INTRODUCTION Blood is the predominant source for molecular analyses in humans, both in
clinical and research settings, and is the target for many therapeutic strategies, emphasizing …
clinical and research settings, and is the target for many therapeutic strategies, emphasizing …
The methyltransferase METTL3 negatively regulates nonalcoholic steatohepatitis (NASH) progression
X Li, B Yuan, M Lu, Y Wang, N Ding, C Liu… - Nature …, 2021 - nature.com
Nonalcoholic steatohepatitis (NASH) is a key step in the progression of nonalcoholic fatty
liver (NAFL) to cirrhosis. However, the molecular mechanisms of the NAFL-to-NASH …
liver (NAFL) to cirrhosis. However, the molecular mechanisms of the NAFL-to-NASH …
The neXtProt knowledgebase in 2020: data, tools and usability improvements
M Zahn-Zabal, PA Michel, A Gateau… - Nucleic Acids …, 2020 - academic.oup.com
Abstract The neXtProt knowledgebase (https://www. nextprot. org) is an integrative resource
providing both data on human protein and the tools to explore these. In order to provide …
providing both data on human protein and the tools to explore these. In order to provide …
Genotype‐Phenotype Relations for the Parkinson's Disease Genes Parkin, PINK1, DJ1: MDSGene Systematic Review
This first comprehensive MDSGene review is devoted to the 3 autosomal recessive
Parkinson's disease forms: PARK‐Parkin, PARK‐PINK1, and PARK‐DJ1. It followed …
Parkinson's disease forms: PARK‐Parkin, PARK‐PINK1, and PARK‐DJ1. It followed …
How many human proteoforms are there?
Despite decades of accumulated knowledge about proteins and their post-translational
modifications (PTMs), numerous questions remain regarding their molecular composition …
modifications (PTMs), numerous questions remain regarding their molecular composition …
ProteomicsDB
Abstract ProteomicsDB (https://www. ProteomicsDB. org) is a protein-centric in-memory
database for the exploration of large collections of quantitative mass spectrometry-based …
database for the exploration of large collections of quantitative mass spectrometry-based …